Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 11/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.32 |
| ▸ | KDR | P35968 | 3/20 | 0.32 |
| ▸ | KIT | P10721 | 2/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469592 | 0.87 | BTK (0.44) | BTKFLT3KDRKITCSF1R | |
| SCHEMBL12469585 | 0.85 | BTK (0.45) | BTKFLT3CSF1R | |
| SCHEMBL12469587 | 0.84 | BTK (0.43) | BTKFLT3GRIN2BCSF1R | |
| SCHEMBL12469269 | 0.84 | BTK (0.46) | BTKFLT3KDRCSF1R | |
| SCHEMBL12469852 | 0.83 | BTK (0.42) | BTKFLT3CSF1R | |
| SCHEMBL1292440 | 0.82 | BTK (0.42) | BTKFLT3PDGFRBKDRKIT | |
| SCHEMBL12469665 | 0.82 | BTK (0.46) | BTKFLT3KDRCSF1R | |
| SCHEMBL12469483 | 0.81 | BTK (0.39) | BTKFLT3PDGFRBKDRKIT | |
| SCHEMBL12469588 | 0.81 | BTK (0.43) | BTKFLT3CSF1R | |
| SCHEMBL12469500 | 0.79 | BTK (0.42) | BTKFLT3CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047017-A2 | 2,3-DIHYDRO-ISOINDOL-1-ONE DERIVATIVE AND A COMPOSITION COMPRISING THE SAME | 크리스탈지노믹스(주) (KR) | 2012-04-12 | — | — | WO | disclosed |