Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 11/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 3/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.32 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.32 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469500 | 0.93 | BTK (0.42) | BTKFLT3CSF1RMAP4K1CYP1A2 | |
| SCHEMBL12469722 | 0.91 | BTK (0.42) | BTKFLT3CSF1RPDE7APIM1 | |
| SCHEMBL12469665 | 0.89 | BTK (0.46) | BTKFLT3CSF1RPDE7APIM1 | |
| SCHEMBL12469585 | 0.88 | BTK (0.45) | BTKFLT3CSF1RPDE7A | |
| SCHEMBL12469479 | 0.87 | BTK (0.44) | BTKFLT3CSF1RPIM1PIM2 | |
| SCHEMBL12469592 | 0.86 | BTK (0.44) | BTKFLT3CSF1RPDE7APIM1 | |
| SCHEMBL12469852 | 0.84 | BTK (0.42) | BTKFLT3CSF1R | |
| SCHEMBL12469587 | 0.83 | BTK (0.43) | BTKFLT3CSF1RCYP2D6KCNH2 | |
| SCHEMBL1292735 | 0.82 | BTK (0.54) | BTKFLT3 | |
| SCHEMBL12469269 | 0.82 | BTK (0.46) | BTKFLT3CSF1RPIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047017-A2 | 2,3-DIHYDRO-ISOINDOL-1-ONE DERIVATIVE AND A COMPOSITION COMPRISING THE SAME | 크리스탈지노믹스(주) (KR) | 2012-04-12 | — | — | WO | disclosed |