Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 11/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 3/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469479 | 0.96 | BTK (0.44) | BTKFLT3CSF1RPIM1PIM2 | |
| SCHEMBL12469500 | 0.93 | BTK (0.42) | BTKFLT3CSF1RPDE7APIM1 | |
| SCHEMBL12469588 | 0.91 | BTK (0.43) | BTKFLT3CSF1RPDE7APIM1 | |
| SCHEMBL12469665 | 0.88 | BTK (0.46) | BTKFLT3CSF1RPDE7APIM1 | |
| SCHEMBL12469592 | 0.86 | BTK (0.44) | BTKFLT3CSF1RPDE7APIM1 | |
| SCHEMBL12469585 | 0.86 | BTK (0.45) | BTKFLT3CSF1RPDE7A | |
| SCHEMBL12469475 | 0.84 | BTK (0.46) | BTKFLT3CSF1R | |
| SCHEMBL12469852 | 0.83 | BTK (0.42) | BTKFLT3CSF1RDPP4 | |
| SCHEMBL12469269 | 0.82 | BTK (0.46) | BTKFLT3CSF1RPIM1PIM2 | |
| SCHEMBL12469587 | 0.82 | BTK (0.43) | BTKFLT3CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047017-A2 | 2,3-DIHYDRO-ISOINDOL-1-ONE DERIVATIVE AND A COMPOSITION COMPRISING THE SAME | 크리스탈지노믹스(주) (KR) | 2012-04-12 | — | — | WO | disclosed |