Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | GID4 | Q8IVV7 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13987850 | 0.72 | PRCP (0.36) | HSD17B10SIGMAR1GID4KMT2AHTR2C | |
| SCHEMBL14095705 | 0.72 | PRCP (0.36) | HSD17B10SIGMAR1GID4KMT2AHTR2C | |
| SCHEMBL3653136 | 0.68 | SIGMAR1 (0.42) | SIGMAR1RAB9AHTR2CPRCPGAA | |
| SCHEMBL14192246 | 0.63 | CYP3A4 (0.64) | HSD17B10CYP3A4TAAR1TDP1NPC1 | |
| Biphenyl SCHEMBL3671251 | 0.62 | CYP3A4 (0.93) | HSD17B10CYP3A4TAAR1TDP1NPC1 | |
| SCHEMBL24524183 | 0.60 | CYP3A4 (1.00) | HSD17B10CYP3A4TAAR1TDP1NPC1 | |
| Biphenyl-4-Amine SCHEMBL15921057 | 0.60 | CYP3A4 (1.00) | HSD17B10CYP3A4TAAR1TDP1NPC1 | |
| SCHEMBL21392391 | 0.60 | CYP3A4 (1.00) | HSD17B10CYP3A4TAAR1TDP1NPC1 | |
| Benzidine SCHEMBL308333 | 0.60 | CYP3A4 (1.00) | HSD17B10CYP3A4TAAR1TDP1NPC1 | |
| Biphenyl-4-Amine SCHEMBL20296849 | 0.60 | CYP3A4 (1.00) | HSD17B10CYP3A4TAAR1TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627651-A1 | ANTI-VIRAL COMPOUNDS | Abbvie Inc. (US) | 2013-08-21 | — | — | EP | disclosed |
| WO-2012051361-A1 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2012-04-19 | — | — | WO | disclosed |