Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29581362 | 0.87 | MMP2 (0.34) | MMP2ANPEPPIN1ATM | |
| SCHEMBL29489453 | 0.87 | MMP2 (0.34) | MMP2ANPEPPIN1ATM | |
| SCHEMBL29253522 | 0.85 | ATM (0.43) | MMP2ANPEPUCHL1ATM | |
| SCHEMBL2770048 | 0.85 | ATM (0.43) | MMP2ANPEPUCHL1ATM | |
| SCHEMBL19064872 | 0.85 | ATM (0.43) | MMP2ANPEPUCHL1ATM | |
| SCHEMBL3440720 | 0.85 | ATM (0.43) | MMP2ANPEPUCHL1ATM | |
| SCHEMBL6596413 | 0.85 | ATM (0.43) | MMP2ANPEPUCHL1ATM | |
| SCHEMBL5160994 | 0.85 | ATM (0.43) | MMP2ANPEPUCHL1ATM | |
| SCHEMBL25304982 | 0.84 | ATM (0.34) | MMP2ANPEPUCHL1ATM | |
| SCHEMBL25303244 | 0.84 | ATM (0.34) | MMP2ANPEPUCHL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2678334-A1 | ANTI-VIRAL COMPOUNDS | Abbvie Inc. (US) | 2014-01-01 | — | — | EP | disclosed |
| EP-2627651-A1 | ANTI-VIRAL COMPOUNDS | Abbvie Inc. (US) | 2013-08-21 | — | — | EP | disclosed |
| WO-2012116257-A1 | ANTI-VIRAL COMPOUNDS | ABBVIE INC. (US) | 2012-08-30 | — | — | WO | disclosed |
| WO-2012051361-A1 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2012-04-19 | — | — | WO | disclosed |