Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.48 |
| ▸ | CIT | O14578 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6260764 | 0.81 | TAAR1 (0.67) | TAAR1L3MBTL1ALDH1A1CITGAA | |
| SCHEMBL1751436 | 0.76 | TAAR1 (1.00) | TAAR1ALDH1A1CITNPC1RAB9A | |
| SCHEMBL4652086 | 0.76 | TAAR1 (1.00) | TAAR1ALDH1A1CITNPC1RAB9A | |
| SCHEMBL4059859 | 0.75 | MAPT (0.49) | L3MBTL1ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL18731749 | 0.74 | CYP1A2 (0.58) | ALDH1A1 | |
| SCHEMBL1104820 | 0.74 | CYP1A2 (0.62) | ALDH1A1 | |
| SCHEMBL28129147 | 0.73 | CYP1A2 (0.53) | L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL28317085 | 0.73 | CYP1A2 (0.56) | ALDH1A1GAANPC1RAB9AMEN1 | |
| Iodide SCHEMBL30847747 | 0.73 | CYP1A2 (0.60) | ALDH1A1 | |
| SCHEMBL4741417 | 0.72 | TAAR1 (0.79) | TAAR1ALDH1A1GAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459734-B1 | NOVEL PEPTIDASE SUBSTRATES | BIOMERIEUX SA (FR) | 2014-10-08 | — | — | EP | claimed |
| US-8592174-B2 | Peptidase substrates | bioMérieux, S.A. (FR) | 2013-11-26 | — | — | US | claimed |
| EP-2459734-A2 | NOVEL PEPTIDASE SUBSTRATES | Biomérieux (FR) | 2012-06-06 | — | — | EP | claimed |
| US-20120122135-A1 | Novel Peptidase Substrates | bioMerieux, SA (FR) | 2012-05-17 | — | — | US | claimed |
| WO-2011012809-A2 | NOVEL PEPTIDASE SUBSTRATES | bioMérieux (FR) | 2011-02-03 | — | — | WO | claimed |
| EP-2459734-B1 | NOVEL PEPTIDASE SUBSTRATES | BIOMERIEUX SA (FR) | 2014-10-08 | — | — | EP | disclosed |
| US-8592174-B2 | Peptidase substrates | bioMérieux, S.A. (FR) | 2013-11-26 | — | — | US | disclosed |
| EP-2459734-A2 | NOVEL PEPTIDASE SUBSTRATES | Biomérieux (FR) | 2012-06-06 | — | — | EP | disclosed |
| US-20120122135-A1 | Novel Peptidase Substrates | bioMerieux, SA (FR) | 2012-05-17 | — | — | US | disclosed |
| WO-2011012809-A2 | NOVEL PEPTIDASE SUBSTRATES | bioMérieux (FR) | 2011-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122135-A1 | Novel Peptidase Substrates | CPN1, CTRL, ANPEP | TAAR1 939/4885L3MBTL1 1347/4885ALDH1A1 2722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.