Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | CIT | O14578 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5273543 | 0.84 | CIT (0.50) | TAAR1ALDH1A1GAACITKDM4E | |
| SCHEMBL29226582 | 0.81 | KMT2A (0.68) | TAAR1ALDH1A1KDM4EKMT2APOLB | |
| SCHEMBL1246982 | 0.81 | TAAR1 (0.59) | TAAR1ALDH1A1GAALTA4HCIT | |
| SCHEMBL4652086 | 0.81 | TAAR1 (1.00) | TAAR1ALDH1A1LTA4HIDO1CIT | |
| SCHEMBL1751436 | 0.81 | TAAR1 (1.00) | TAAR1ALDH1A1LTA4HIDO1CIT | |
| SCHEMBL5273957 | 0.80 | ACHE (0.63) | TAAR1LTA4HIDO1CITXIAP | |
| SCHEMBL5278210 | 0.80 | TAAR1 (0.53) | TAAR1ALDH1A1GAALTA4HIDO1 | |
| Hydrochloric Acid SCHEMBL5404008 | 0.79 | ACHE (0.62) | TAAR1LTA4HIDO1CITXIAP | |
| Hydrochloric Acid SCHEMBL5414835 | 0.78 | ACHE (0.60) | TAAR1LTA4HIDO1CITXIAP | |
| SCHEMBL5273024 | 0.78 | JAK2 (0.50) | ALDH1A1GAAKDM4EKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1587793-A1 | ENZYME SUBSTRATES, CULTURE MEDIA CONTAINING SAME AND USE THEREOF IN ORDER TO DETECT AMINOPEPTIDASE ACTIVITY AND/OR DIFFERENTIATE GRAM-POSITIVE BACTERIA FROM GRAM-NEGATIVE BACTERIA | BIOMERIEUX (FR) | 2005-10-26 | — | — | EP | disclosed |
| WO-2004069804-A1 | ENZYME SUBSTRATES, CULTURE MEDIA CONTAINING SAME AND USE THEREOF IN ORDER TO DETECT AMINOPEPTIDASE ACTIVITY AND/OR DIFFERENTIATE GRAM-POSITIVE BACTERIA FROM GRAM-NEGATIVE BACTERIA | BIOMERIEUX (FR) | 2004-08-19 | — | — | WO | disclosed |