Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | USP2 | O75604 | 1/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | GALR3 | O60755 | 1/20 | 0.59 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.58 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1971770 | 0.88 | MAPK1 (1.00) | MAPK1L3MBTL1ALDH1A1USP2NPSR1 | |
| SCHEMBL14082550 | 0.87 | SMN1; SMN2 (0.77) | MAPK1L3MBTL1ALDH1A1USP2NPSR1 | |
| SCHEMBL582322 | 0.84 | SMN1; SMN2 (0.85) | L3MBTL1ALDH1A1SMN1; SMN2RECQLLMNA | |
| SCHEMBL5083625 | 0.83 | KMT2A (0.77) | USP2TSHRNPC1 | |
| SCHEMBL12078119 | 0.81 | LMNA (0.79) | L3MBTL1ALDH1A1USP2NPSR1CYP3A4 | |
| SCHEMBL10882130 | 0.81 | MAPK1 (0.65) | MAPK1L3MBTL1ALDH1A1USP2NPSR1 | |
| SCHEMBL2798817 | 0.81 | MAPK1 (0.58) | MAPK1L3MBTL1ALDH1A1USP2NPSR1 | |
| SCHEMBL13779327 | 0.80 | POLB (0.67) | MAPK1L3MBTL1ALDH1A1USP2NPSR1 | |
| SCHEMBL4298914 | 0.79 | BCHE (0.63) | L3MBTL1ALDH1A1USP2NPSR1SMN1; SMN2 | |
| SCHEMBL13622870 | 0.79 | BCHE (0.63) | L3MBTL1ALDH1A1USP2NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2286221-A2 | METHODS FOR ASSAYING COMPOUNDS OR AGENTS FOR ABILITY TO DISPLACE POTENT LIGANDS OF HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE | Cayman Chemical Company (US) | 2011-02-23 | — | — | EP | disclosed |