Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | PARL | Q9H300 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28243714 | 0.81 | TDP1 (0.43) | TDP1ALDH1A1HSD17B10HTR6PARL | |
| SCHEMBL14778409 | 0.79 | HTR6 (0.46) | TDP1ALDH1A1HSD17B10HTR6PARL | |
| SCHEMBL28465973 | 0.78 | GAA (0.48) | TDP1ALDH1A1MAPTKMT2ACA1 | |
| SCHEMBL113891 | 0.77 | HTR6 (0.44) | TDP1ALDH1A1HSD17B10HTR6PARL | |
| SCHEMBL9797090 | 0.77 | HTR6 (0.44) | TDP1ALDH1A1HSD17B10HTR6PARL | |
| SCHEMBL780154 | 0.77 | HTR6 (0.44) | TDP1ALDH1A1HSD17B10HTR6PARL | |
| SCHEMBL7534473 | 0.77 | HTR6 (0.44) | TDP1ALDH1A1HSD17B10HTR6PARL | |
| Water SCHEMBL28177511 | 0.77 | GAA (0.46) | TDP1ALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL3634121 | 0.77 | CA12 (0.46) | TDP1ALDH1A1HSD17B10HTR6PARL | |
| SCHEMBL14780300 | 0.76 | HTR6 (0.42) | TDP1ALDH1A1HSD17B10HTR6PARL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283005-A2 | CISATRACURIUM DERIVATIVES, PREPARATION AND USES THEREOF | Chemagis Ltd. (IL) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009133556-A2 | CISATRACURIUM DERIVATIVES, PREPARATION AND USES THEREOF | CHEMAGIS LTD. (IL) | 2009-11-05 | — | — | WO | disclosed |