Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12472394 | 0.89 | — | — | |
| SCHEMBL10144470 | 0.83 | PDE10A (0.43) | PDE10A | |
| SCHEMBL10835168 | 0.83 | PDE10A (0.43) | PDE10A | |
| SCHEMBL12472395 | 0.80 | — | — | |
| SCHEMBL582880 | 0.78 | ERBB2 (0.31) | PDE10A | |
| SCHEMBL7154330 | 0.76 | PDE10A (0.36) | PDE10A | |
| SCHEMBL10052570 | 0.71 | ERBB2 (0.32) | — | |
| SCHEMBL6129973 | 0.70 | NOS3 (0.37) | PDE10A | |
| SCHEMBL11329592 | 0.69 | MAPK1 (0.34) | PDE10A | |
| SCHEMBL3457245 | 0.69 | MAPK1 (0.32) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101143851-A | Ligustrazine aromatic acid ether derivatives, preparation method thereof, medicament composition and use | LI JIAMING HE GUANGWEI (CN) | 2008-03-19 | — | — | CN | claimed |
| CN-116675724-A | Tripterine-ligustrazine hybrid, and preparation method and application thereof | 安徽理工大学 | 2023-09-01 | — | — | CN | disclosed |
| CN-105315321-A | Compound having antitumor effect, preparation method and application thereof | LEI HAIMIN | 2016-02-10 | — | — | CN | disclosed |
| CN-103664804-B | Pirodomast analogue, preparation method and application thereof | ANHUI UNIVERSITY OF CHINESE MEDICINE (CN) | 2016-01-20 | — | — | CN | disclosed |
| CN-105153049-A | Tanshinol amide derivative and preparation method and application thereof | UNIV HEFEI TECHNOLOGY | 2015-12-16 | — | — | CN | disclosed |
| CN-102653539-B | Compound for resisting platelet aggregation and medicament combination thereof | QIN YINLIN | 2014-09-17 | — | — | CN | disclosed |
| CN-103664804-A | Picotamide analogues as well as preparation method and application thereof | ANHUI UNIVERSITY OF CHINESE MEDICINE | 2014-03-26 | — | — | CN | disclosed |
| CN-102225896-B | Ether derivatives of rhein and their therapeutic use | LI JINCAI | 2013-10-30 | — | — | CN | disclosed |
| CN-103360408-A | Novel thienopyridine compounds and use thereof in medicine | INST PHARM & TOXICOLOGY AMMS | 2013-10-23 | — | — | CN | disclosed |
| CN-102225913-B | Rheinic acid derivatives and treatment application thereof | LI JINCAI | 2013-09-04 | — | — | CN | disclosed |
| CN-102653539-A | Compound for resisting platelet aggregation and medicament combination thereof | YINLIN QIN | 2012-09-05 | — | — | CN | disclosed |
| WO-2012103813-A1 | DANSHENSU AND CHUANXIONGQIN DERIVATIVES, PROCESS FOR PREPARATION, AND USE THEREOF | JINAN UNIVERSITY (CN) | 2012-08-09 | — | — | WO | disclosed |
| CN-102225913-A | Rheinic acid derivatives and treatment application thereof | JINCAI LI | 2011-10-26 | — | — | CN | disclosed |
| CN-102225896-A | Ether derivatives of rhein and their therapeutic use | JINCAI LI | 2011-10-26 | — | — | CN | disclosed |
| CN-101012201-B | Ligustrazine derivative, preparation method and medical use thereof | UNIV CHINA PHARMA | 2010-07-28 | — | — | CN | disclosed |
| CN-101143851-B | Ligustrazine aromatic acid ether derivatives, preparation method thereof, medicament composition and use | GUANGWEI HE | 2010-07-21 | — | — | CN | disclosed |
| CN-101143851-A | Ligustrazine aromatic acid ether derivatives, preparation method thereof, medicament composition and use | LI JIAMING HE GUANGWEI (CN) | 2008-03-19 | — | — | CN | disclosed |
| CN-101012201-A | Ligustrazine derivative, preparation method and medical use thereof | UNIV CHINA PHARMA (CN) | 2007-08-08 | — | — | CN | disclosed |
| CN-1640870-A | Ibuprofen ester, medically-acceptable salt, and its preparing process and medicinal composition | HUATAI MEDICINE RES CO LTD SHE (CN) | 2005-07-20 | — | — | CN | disclosed |