SCHEMBL12471815

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4137247	0.84	KDM4E (0.66)	KDM4EGABBR2GABBR1CYP1A2ALDH1A1
	SCHEMBL1398393	0.83	CES1 (0.59)	KDM4EMEN1KMT2AGAAMAPT
	SCHEMBL4153130	0.81	KDM4E (0.62)	KDM4EGABBR2GABBR1CYP1A2ALDH1A1
	SCHEMBL2500212	0.81	CES1 (0.65)	KDM4EALDH1A1MEN1KMT2ANPC1
	SCHEMBL30214744	0.81	CES1 (0.65)	KDM4EALDH1A1MEN1KMT2ANPC1
	SCHEMBL10899760	0.80	KDM4E (0.60)	KDM4EGABBR2GABBR1CYP1A2ALDH1A1
	SCHEMBL11810869	0.80	KDM4E (0.75)	KDM4ECYP1A2ALDH1A1HPGDCYP2C19
	SCHEMBL2695583	0.79	KDM4E (0.58)	KDM4EGABBR2GABBR1CYP1A2ALDH1A1
	SCHEMBL2695581	0.79	KDM4E (0.58)	KDM4EGABBR2GABBR1CYP1A2ALDH1A1
	SCHEMBL8132	0.78	KDM4E (1.00)	KDM4ECYP1A2ALDH1A1HPGDCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.