SCHEMBL8132

SCHEMBL8132

COc1ccc2cc(C(=O)O)ccc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 1.00
CA1 P00915 2/20 0.67
CA2 P00918 2/20 0.67
CYP1A2 P05177 3/20 0.65
ALDH1A1 P00352 2/20 0.65
HPGD P15428 1/20 0.65
CYP2C19 P33261 1/20 0.65
HSD17B10 Q99714 1/20 0.65
AKR1C3 P42330 4/20 0.56
AKR1C2 P52895 4/20 0.56
PTGS1 P23219 3/20 0.56
PLAU P00749 1/20 0.55
CA12 O43570 1/20 0.55
CA4 P22748 1/20 0.55
CA6 P23280 1/20 0.55
CA7 P43166 1/20 0.55
TPMT P51580 1/20 0.55
CA9 Q16790 1/20 0.55
CA14 Q9ULX7 1/20 0.55
RXRA P19793 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34463427 1.00 KDM4E (1.00) KDM4ECA1CA2CYP1A2ALDH1A1
Hydrochloric Acid SCHEMBL3541422 0.98 KDM4E (0.96) KDM4ECA1CA2CYP1A2ALDH1A1
SCHEMBL5875335 0.98 KDM4E (0.96) KDM4ECA1CA2CYP1A2ALDH1A1
SCHEMBL1145072 0.96 KDM4E (0.93) KDM4ECA1CA2CYP1A2ALDH1A1
SCHEMBL8461552 0.94 KDM4E (0.89) KDM4ECA1CA2CYP1A2ALDH1A1
Cyanide SCHEMBL11199466 0.94 KDM4E (0.89) KDM4ECA1CA2CYP1A2ALDH1A1
SCHEMBL7560634 0.89 KDM4E (0.80) KDM4ECA1CA2CYP1A2ALDH1A1
Methoxymethane SCHEMBL6861468 0.87 KDM4E (0.77) KDM4ECA1CA2CYP1A2ALDH1A1
SCHEMBL8459975 0.87 KDM4E (0.77) KDM4ECA1CA2CYP1A2ALDH1A1
SCHEMBL9702751 0.87 KDM4E (0.77) KDM4ECA1CA2CYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 416 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119841727-A Method for directly preparing carboxylic ester compound from aromatic aldehyde, ketone and carboxylic acid 湖南第一师范学院 2025-04-18 CN claimed
CN-119799320-A Organic narrow-band afterglow material based on halation benzene derivative and preparation and application methods thereof 中国科学院上海有机化学研究所 2025-04-11 CN claimed
CN-119638770-A Clobetasol propionate derivative and preparation method thereof 复旦大学 2025-03-18 CN claimed
CN-119528737-A Small molecular compound DHN and preparation method and application thereof 厦门大学 2025-02-28 CN claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-116836081-A Ether epoxy toughening agent and preparation method and application thereof 中国林业科学研究院林产化学工业研究所 2023-10-03 CN claimed
US-10191398-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2019-01-29 US claimed
EP-2463345-B1 Ink composition, recording method using the same and recorded material SEIKO EPSON CORP (JP) 2017-01-18 EP claimed
EP-1749864-B1 INK COMPOSITION, AND INK JET RECORDING METHOD AND RECORDED MATTER USING THE SAME SEIKO EPSON CORP (JP) 2015-07-22 EP claimed
EP-1676891-B1 INK COMPOSITION AND INKJET RECORDING METHOD AND RECORDED MATTER USING THE SAME SEIKO EPSON CORP (JP) 2015-05-27 EP claimed
US-6984032-B2 Ink composition, ink set, recording process and recorded matter SEIKO EPSON CORPORATION (JP) 2006-01-10 US claimed
US-20050115459-A1 Magenta ink composition SEIKO EPSON CORPORATION 2005-06-02 US claimed
US-20040259930-A1 Linear basic compounds having nk-2 antagonist activity and formulations thereof MALESCI INSTITUTO FARMACOBIOLOGICO S.P.A. (IT) 2004-12-23 US claimed
US-20040174420-A1 Ink composition, ink set, recording process and recorded matter SEIKO EPSON CORPORATION 2004-09-09 US claimed
US-20040003755-A1 Ink composition, inkjet recording method using the same and recorded matter SEIKO EPSON CORPORATION 2004-01-08 US claimed
EP-1357158-A1 Ink composition, inkjet recording method using the same and recorded matter SEIKO EPSON CORPORATION (JP) 2003-10-29 EP claimed
WO-2002000651-A2 FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2002-01-03 WO claimed
US-6180830-B1 REDUCING COMPLEX OF RUTHENIUM HAVING ELECTROVALENCY OF-4 AND COORDINATION NUMBER OF 6, WHEREIN AT LEAST ONE LIGAND IS TIN HALIDE, OTHER LIGANDS OPTIONALLY BEING HALOGEN ATOMS RHODIA CHIMIE (FR) 2001-01-30 US claimed
EP-0700890-B1 Process for the preparation of aldehydes by the catalytic vapour phase hydrogenation of carboxylic acids or their derivatives using a tin catalyst AVENTIS RES & TECH GMBH & CO (DE) 1999-12-01 EP claimed
US-5585523-A APPLYING TIN CATALYST TO OXIDE SUPPORT TO FORM CATALYST, HYDROGENATING ACID IN THE PRESENCE OF CATALYST HOECHST AKTIENGESELLSCHAFT (DE) 1996-12-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040259930-A1 Linear basic compounds having nk-2 antagonist activity and formulations thereof BDKRB2, BDKRB1, TACR2 KDM4E 3285/4885CA1 879/4885CA2 471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.