Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | CD74 | P04233 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CLK3 | P49761 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.38 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12473317 | 0.93 | KDM4E (0.42) | KMT2AMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL12473406 | 0.91 | CD74 (0.37) | KMT2AMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL12473321 | 0.91 | CD74 (0.41) | KMT2AMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL12473410 | 0.87 | PRMT7 (0.35) | KMT2AMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL12473398 | 0.87 | PDE10A (0.37) | KMT2AMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL12473199 | 0.87 | CNR2 (0.37) | KMT2AMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL12473412 | 0.87 | MAOB (0.38) | MAPTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL12473402 | 0.87 | NPC1 (0.41) | KMT2AMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL12473396 | 0.83 | NPC1 (0.36) | KMT2AMAPTALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL12473319 | 0.82 | PRMT7 (0.35) | KMT2AMAPTKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046207-A1 | ANTI-PARASITIC SUBSTITUTED RING FUSED AZINE COMPOUNDS | PARACO TECHNOLOGY LIMITED (NZ) | 2012-04-12 | — | — | WO | disclosed |