Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | EIF4A1 | P60842 | 2/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12473400 | 0.93 | RAB9A (0.36) | NPC1RAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL12473410 | 0.85 | PRMT7 (0.35) | NPC1RAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL12473398 | 0.85 | PDE10A (0.37) | NPC1RAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL12473402 | 0.84 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL12473199 | 0.84 | CNR2 (0.37) | NPC1RAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL12473412 | 0.84 | MAOB (0.38) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL12473194 | 0.83 | ALDH1A1 (0.36) | NPC1RAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL12473441 | 0.83 | KMT2A (0.42) | SMN1; SMN2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL12473277 | 0.82 | MAPT (0.35) | NPC1RAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL12473406 | 0.81 | CD74 (0.37) | RAB9ASMN1; SMN2MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046207-A1 | ANTI-PARASITIC SUBSTITUTED RING FUSED AZINE COMPOUNDS | PARACO TECHNOLOGY LIMITED (NZ) | 2012-04-12 | — | — | WO | disclosed |