Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 9/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 9/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 9/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 9/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 9/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 9/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NPFFR1 | Q9GZQ6 | 3/20 | 0.33 |
| ▸ | NPFFR2 | Q9Y5X5 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25468160 | 0.84 | GRIN2D (0.49) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL12120925 | 0.81 | GRIN2D (0.58) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Resomelagon SCHEMBL12123977 | 0.80 | KMT2A (0.45) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1319896 | 0.76 | GAA (0.42) | HTTKMT2AGAA | |
| SCHEMBL1319894 | 0.76 | GAA (0.42) | HTTKMT2AGAA | |
| SCHEMBL12123691 | 0.75 | GRIN2D (0.47) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL12123803 | 0.74 | GRIN2D (0.46) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL12123635 | 0.72 | KDM4E (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL12657546 | 0.72 | GRIN2D (0.39) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL12123918 | 0.69 | GRIN2D (0.36) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348016-B1 | Phenyl pyrrole aminoguanidine derivatives | SYNACT PHARMA APS (DK) | 2016-02-17 | — | — | EP | disclosed |
| EP-2348016-A1 | Phenyl pyrrole aminoguanidine derivatives | Action Pharma A/S (DK) | 2011-07-27 | — | — | EP | disclosed |
| EP-2035373-B1 | PHENYL PYRROLE AMINOGUANIDINE DERIVATIVES | ACTION PHARMA AS (DK) | 2011-05-04 | — | — | EP | disclosed |