Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1319896 | 1.00 | GAA (0.42) | GAAATMALDH1A1TRPA1LMNA | |
| SCHEMBL1321565 | 0.83 | GAA (0.58) | GAAATMALDH1A1MGLLKMT2A | |
| SCHEMBL12120933 | 0.76 | ATM (0.67) | GAAATMALDH1A1TRPA1LMNA | |
| SCHEMBL1322135 | 0.76 | KMT2A (0.56) | GAAATMALDH1A1LMNAMAPK1 | |
| SCHEMBL1322136 | 0.76 | KMT2A (0.56) | GAAATMALDH1A1LMNAMAPK1 | |
| SCHEMBL12473973 | 0.76 | GRIN2D (0.49) | GAAKMT2AHTT | |
| SCHEMBL28817910 | 0.70 | ALDH1A1 (0.49) | GAAATMALDH1A1TRPA1LMNA | |
| SCHEMBL28817922 | 0.70 | POLB (0.38) | GAAATMALDH1A1TRPA1LMNA | |
| SCHEMBL4003906 | 0.69 | PKM (0.49) | GAAATMALDH1A1LMNAMAPK1 | |
| SCHEMBL4004085 | 0.67 | ATM (0.45) | ATMALDH1A1LMNAMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348016-B1 | Phenyl pyrrole aminoguanidine derivatives | SYNACT PHARMA APS (DK) | 2016-02-17 | — | — | EP | disclosed |
| EP-2348016-B1 | Phenyl pyrrole aminoguanidine derivatives | SYNACT PHARMA APS (DK) | 2016-02-17 | — | — | EP | disclosed |
| US-8058306-B2 | Phenyl pyrrole aminoguanidine derivatives | ACTION PHARMA A/S (DK) | 2011-11-15 | — | — | US | disclosed |
| US-8058306-B2 | Phenyl pyrrole aminoguanidine derivatives | ACTION PHARMA A/S (DK) | 2011-11-15 | — | — | US | disclosed |
| EP-2348016-A1 | Phenyl pyrrole aminoguanidine derivatives | Action Pharma A/S (DK) | 2011-07-27 | — | — | EP | disclosed |
| EP-2348016-A1 | Phenyl pyrrole aminoguanidine derivatives | Action Pharma A/S (DK) | 2011-07-27 | — | — | EP | disclosed |
| EP-2035373-B1 | PHENYL PYRROLE AMINOGUANIDINE DERIVATIVES | ACTION PHARMA AS (DK) | 2011-05-04 | — | — | EP | disclosed |
| EP-2035373-B1 | PHENYL PYRROLE AMINOGUANIDINE DERIVATIVES | ACTION PHARMA AS (DK) | 2011-05-04 | — | — | EP | disclosed |
| US-20110082183-A1 | PHENYL PYRROLE AMINOGUANIDINE DERIVATIVES | ACTION PHARMA A/S (DK) | 2011-04-07 | — | — | US | disclosed |
| US-20110082183-A1 | PHENYL PYRROLE AMINOGUANIDINE DERIVATIVES | ACTION PHARMA A/S (DK) | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110082183-A1 | PHENYL PYRROLE AMINOGUANIDINE DERIVATIVES | MC1R, MC5R, MC4R | GAA 1373/4885ATM 3703/4885ALDH1A1 2301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.