Anwuweizonic Acid

Anwuweizonic Acid

SCHEMBL12474243

C/C(=C\CC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CCC(=O)C(C)(C)C1CC3)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 1.00
MEN1 O00255 1/20 1.00
PLA2G1B P04054 1/20 1.00
DNMT1 P26358 1/20 1.00
BLM P54132 1/20 1.00
KMT2A Q03164 1/20 1.00
ATG4B Q9Y4P1 1/20 1.00
FNTA P49354 1/20 0.83
FNTB P49356 1/20 0.83
PTGES O14684 1/20 0.73
PREP P48147 1/20 0.73
PIN1 Q13526 1/20 0.73
CRYAB P02511 2/20 0.66
MAPK1 P28482 1/20 0.65
HMGCR P04035 1/20 0.62
USP2 O75604 2/20 0.61
ALDH1A1 P00352 2/20 0.61
CYP3A4 P08684 2/20 0.61
ALOX15 P16050 2/20 0.61
LMNA P02545 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anwuweizonic Acid SCHEMBL29934311 1.00 MAPT (1.00) MAPTMEN1PLA2G1BDNMT1BLM
Anwuweizonic Acid SCHEMBL20990961 1.00 MAPT (1.00) MAPTMEN1PLA2G1BDNMT1BLM
Anwuweizonic Acid SCHEMBL29934343 1.00 MAPT (1.00) MAPTMEN1PLA2G1BDNMT1BLM
Anwuweizonic Acid SCHEMBL18687709 1.00 MAPT (1.00) MAPTMEN1PLA2G1BDNMT1BLM
Anwuweizonic Acid SCHEMBL12474223 1.00 MAPT (1.00) MAPTMEN1PLA2G1BDNMT1BLM
Anwuweizonic Acid SCHEMBL12474225 1.00 MAPT (1.00) MAPTMEN1PLA2G1BDNMT1BLM
Anwuweizonic Acid SCHEMBL6567253 1.00 MAPT (1.00) MAPTMEN1PLA2G1BDNMT1BLM
SCHEMBL899356 0.91 FNTA (1.00) MAPTMEN1PLA2G1BDNMT1BLM
SCHEMBL2226302 0.91 FNTA (1.00) MAPTMEN1PLA2G1BDNMT1BLM
SCHEMBL29512020 0.91 FNTA (1.00) MAPTMEN1PLA2G1BDNMT1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9376462-B2 Process for preparing delta-7,9(11) steroids from Ganoderma lucidum and analogs thereof INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2016-06-28 US disclosed
US-20130184244-A1 PROCESS FOR PREPARING DELTA-7,9(11) STEROIDS FROM GANODERMA LUCIDUM AND ANALOGS THEREOF INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2013-07-18 US disclosed
WO-2012044817-A2 PROCESS FOR PREPARING DELTA-7,9(11) STEROIDS FROM GANODERMA LUCIDUM AND ANALOGS THEREOF INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2012-04-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130184244-A1 PROCESS FOR PREPARING DELTA-7,9(11) STEROIDS FROM GANODERMA LUCIDUM AND ANALOGS THEREOF CYP51A1, LSS, ERG28 MAPT 4487/4885MEN1 682/4885PLA2G1B 901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.