⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17491741 | 0.91 | PDPK1 (0.32) | — | |
| SCHEMBL17491735 | 0.91 | MC4R (0.34) | — | |
| SCHEMBL12474344 | 0.90 | MC4R (0.31) | — | |
| SCHEMBL15227148 | 0.79 | PDPK1 (0.34) | — | |
| SCHEMBL900667 | 0.79 | ADORA3 (0.30) | — | |
| SCHEMBL900426 | 0.79 | PDPK1 (0.34) | — | |
| SCHEMBL900541 | 0.78 | ADORA3 (0.35) | — | |
| SCHEMBL900925 | 0.78 | ADORA3 (0.36) | — | |
| SCHEMBL15227388 | 0.76 | HRH3 (0.41) | — | |
| SCHEMBL900280 | 0.75 | HRH3 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621916-A1 | BENZAZOLE DERIVATIVES AS HISTAMINE H4 RECEPTOR LIGANDS | BIOPROJET (FR) | 2013-08-07 | — | — | EP | claimed |
| WO-2012041860-A1 | BENZAZOLE DERIVATIVES AS HISTAMINE H4 RECEPTOR LIGANDS | BIOPROJET (FR) | 2012-04-05 | — | — | WO | claimed |
| EP-2621916-A1 | BENZAZOLE DERIVATIVES AS HISTAMINE H4 RECEPTOR LIGANDS | BIOPROJET (FR) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041860-A1 | BENZAZOLE DERIVATIVES AS HISTAMINE H4 RECEPTOR LIGANDS | BIOPROJET (FR) | 2012-04-05 | — | — | WO | disclosed |