Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 11/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.55 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.51 |
| ▸ | AXL | P30530 | 1/20 | 0.49 |
| ▸ | CKS1B | P61024 | 3/20 | 0.49 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.49 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30925464 | 0.88 | SLC40A1 (0.70) | SLC40A1MEN1KMT2AAGTR1GLO1 | |
| SCHEMBL11973450 | 0.86 | SLC40A1 (1.00) | SLC40A1MEN1KMT2AAGTR1GLO1 | |
| SCHEMBL11973685 | 0.83 | SLC40A1 (0.67) | SLC40A1MEN1KMT2AAGTR1AXL | |
| SCHEMBL7570431 | 0.78 | POLB (0.61) | MEN1KMT2A | |
| SCHEMBL11973253 | 0.77 | SLC40A1 (1.00) | SLC40A1MEN1KMT2AAGTR1GLO1 | |
| SCHEMBL23666285 | 0.76 | SLC40A1 (0.71) | SLC40A1MEN1KMT2AAGTR1GLO1 | |
| SCHEMBL11973628 | 0.75 | SLC40A1 (0.74) | SLC40A1MEN1KMT2AAGTR1CKS1B | |
| SCHEMBL27214176 | 0.75 | SLC40A1 (0.67) | SLC40A1MEN1KMT2AAGTR1GLO1 | |
| SCHEMBL11972882 | 0.75 | SLC40A1 (0.71) | SLC40A1MEN1KMT2AAGTR1TDP1 | |
| SCHEMBL11973534 | 0.74 | SLC40A1 (0.69) | SLC40A1MEN1KMT2AAGTR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-A1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | Vifor (International) AG (CH) | 2013-12-25 | — | — | EP | disclosed |
| WO-2012110603-A1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2012-08-23 | — | — | WO | disclosed |