Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.56 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.55 |
| ▸ | POLB | P06746 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 2/20 | 0.55 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.55 |
| ▸ | NSD2 | O96028 | 1/20 | 0.55 |
| ▸ | ALPL | P05186 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | ALPI | P09923 | 1/20 | 0.55 |
| ▸ | ALPG | P10696 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20005701 | 0.79 | MAPT (0.55) | MAPTALDH1A1MAPK1SAE1UBA2 | |
| SCHEMBL2780507 | 0.72 | MAPT (1.00) | MAPTALDH1A1MAPK1SAE1UBA2 | |
| SCHEMBL3639267 | 0.72 | MAPT (1.00) | MAPTALDH1A1MAPK1SAE1UBA2 | |
| SCHEMBL13657865 | 0.72 | MAPT (1.00) | MAPTALDH1A1MAPK1SAE1UBA2 | |
| SCHEMBL7149412 | 0.72 | KMT2A (0.56) | MAPTALDH1A1MAPK1SAE1UBA2 | |
| SCHEMBL6694241 | 0.71 | ALDH1A1 (0.57) | MAPTALDH1A1MAPK1KMT2APOLB | |
| SCHEMBL6690737 | 0.71 | ALDH1A1 (0.57) | MAPTALDH1A1MAPK1KMT2APOLB | |
| SCHEMBL5866035 | 0.71 | ALDH1A1 (0.57) | MAPTALDH1A1MAPK1KMT2APOLB | |
| SCHEMBL12821631 | 0.69 | MAPT (0.62) | MAPTALDH1A1MAPK1SAE1UBA2 | |
| SCHEMBL10625900 | 0.69 | MEN1 (0.59) | MAPTALDH1A1MAPK1SAE1UBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012109220-A2 | CELL CYCLE CONTROL FOR IMPROVING PROCESS PERFORMANCE AND RECOMBINANT EXPRESSION IN FUNGAL HOST CELLS | MERCK SHARP & DOHME CORP. (US) | 2012-08-16 | — | — | WO | disclosed |