SCHEMBL12475197

SCHEMBL12475197

CC(C)N(C(=O)CCCC(N)=O)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.61
LMNA P02545 3/20 0.61
TP53 P04637 2/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
MLYCD O95822 2/20 0.47
NPSR1 Q6W5P4 1/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
TRPM8 Q7Z2W7 2/20 0.41
ATM Q13315 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1114982 0.89 ALDH1A1 (0.63) ALDH1A1LMNATP53SMN1; SMN2MLYCD
SCHEMBL12856049 0.87 ALDH1A1 (0.61) ALDH1A1LMNATP53SMN1; SMN2MLYCD
SCHEMBL12475281 0.86 ALDH1A1 (0.45) ALDH1A1LMNATP53SMN1; SMN2MLYCD
SCHEMBL12679908 0.86 ALDH1A1 (0.59) ALDH1A1LMNATP53SMN1; SMN2MLYCD
SCHEMBL1114986 0.85 ALDH1A1 (0.63) ALDH1A1LMNATP53SMN1; SMN2MLYCD
SCHEMBL1114751 0.84 ALDH1A1 (0.61) ALDH1A1LMNATP53SMN1; SMN2MLYCD
SCHEMBL1114800 0.84 ALDH1A1 (0.61) ALDH1A1LMNATP53SMN1; SMN2MLYCD
SCHEMBL9321117 0.84 ALDH1A1 (0.61) ALDH1A1LMNATP53SMN1; SMN2MLYCD
SCHEMBL1114834 0.84 ALDH1A1 (0.61) ALDH1A1LMNATP53SMN1; SMN2MLYCD
SCHEMBL1114760 0.84 ALDH1A1 (0.61) ALDH1A1LMNATP53SMN1; SMN2MLYCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2673281-A1 BORON CONTAINING POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTICS USES THEREOF Rempex Pharmaceuticals, Inc. (US) 2013-12-18 EP disclosed
WO-2012109164-A1 BORON CONTAINING POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTICS USES THEREOF REMPEX PHARMACEUTICALS, INC. (US) 2012-08-16 WO disclosed