Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.72 |
| ▸ | HPGD | P15428 | 6/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | STS | P08842 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6589340 | 0.89 | MAOB (0.68) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL3076112 | 0.86 | ALDH1A1 (0.72) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL27582367 | 0.84 | CA12 (0.58) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL7116035 | 0.84 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL6591353 | 0.82 | MAOB (0.70) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL6778357 | 0.81 | ALDH1A1 (0.65) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL9192112 | 0.81 | MAOB (0.62) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL7504934 | 0.80 | ALDH1A1 (0.73) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL17439465 | 0.80 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL6665079 | 0.80 | ALDH1A1 (0.78) | ALDH1A1KDM4EHPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012109495-A1 | CELLULAR TARGETS OF THIAZOLIDINEDIONES | METABOLIC SOLUTIONS DEVELOPMENT COMPANY, LLC (US) | 2012-08-16 | — | — | WO | disclosed |