SCHEMBL12475255

SCHEMBL12475255

CC(C)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)NC(Cc1ccccc1)C(N)CC(=O)O)C(C)C

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CTSD P07339 20/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12475257 1.00 CTSD (0.80) CTSD
SCHEMBL19292281 0.93 CTSD (0.78) CTSD
SCHEMBL19696424 0.92 CTSD (0.80) CTSD
SCHEMBL12475204 0.92 CTSD (0.80) CTSD
SCHEMBL17969275 0.91 CTSD (0.85) CTSD
SCHEMBL17969277 0.91 CTSD (0.85) CTSD
SCHEMBL17969276 0.91 CTSD (0.85) CTSD
SCHEMBL19292625 0.91 CTSD (0.76) CTSD
SCHEMBL19696398 0.89 CTSD (1.00) CTSD
SCHEMBL17770715 0.89 CTSD (1.00) CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2673287-B1 AMINO STATIN DERIVATIVES FOR THE TREATMENT OF ARTHROSIS MERCK PATENT GMBH (DE) 2017-08-30 EP claimed
EP-2673287-A1 AMINO STATIN DERIVATIVES FOR THE TREATMENT OF ARTHROSIS Merck Patent GmbH (DE) 2013-12-18 EP claimed
WO-2012107153-A1 AMINO STATIN DERIVATIVESFOR THE TREATMENT OF ARTHROSIS MERCK PATENT GMBH (DE) 2012-08-16 WO claimed
EP-2673287-B1 AMINO STATIN DERIVATIVES FOR THE TREATMENT OF ARTHROSIS MERCK PATENT GMBH (DE) 2017-08-30 EP disclosed
EP-2673287-A1 AMINO STATIN DERIVATIVES FOR THE TREATMENT OF ARTHROSIS Merck Patent GmbH (DE) 2013-12-18 EP disclosed
WO-2012107153-A1 AMINO STATIN DERIVATIVESFOR THE TREATMENT OF ARTHROSIS MERCK PATENT GMBH (DE) 2012-08-16 WO disclosed