SCHEMBL12475384

SCHEMBL12475384

C1CCC2C(C1)CCC1C2CCC2C3CCCCC3CCC21

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
HSD11B1 P28845 1/20 0.31
HSD11B2 P80365 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1760687 1.00 ALDH1A1 (0.47) ALDH1A1HSD11B1HSD11B2
SCHEMBL29885718 0.97 ALDH1A1 (0.44) ALDH1A1HSD11B1HSD11B2
SCHEMBL29886257 0.97 ALDH1A1 (0.44) ALDH1A1HSD11B1HSD11B2
SCHEMBL15454179 0.97 ALDH1A1 (0.44) ALDH1A1HSD11B1HSD11B2
SCHEMBL375061 0.97 ALDH1A1 (0.44) ALDH1A1HSD11B1HSD11B2
SCHEMBL27526921 0.97 ALDH1A1 (0.44) ALDH1A1HSD11B1HSD11B2
SCHEMBL2724740 0.97 ALDH1A1 (0.44) ALDH1A1HSD11B1HSD11B2
SCHEMBL3774067 0.96 ALDH1A1 (0.50) ALDH1A1HSD11B1HSD11B2
Barium SCHEMBL29897735 0.94 ALDH1A1 (0.41) ALDH1A1
SCHEMBL30595060 0.94 ALDH1A1 (0.41) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9273342-B2 Methods and systems for evaluating and predicting the reactivity of monooxygenase enzymes UNIVERSITY OF ROCHESTER (US) 2016-03-01 US claimed
US-20140038850-A1 METHODS AND SYSTEMS FOR EVALUATING AND PREDICTING THE REACTIVITY OF MONOOXYGENASE ENZYMES UNIVERSITY OF ROCHESTER (US) 2014-02-06 US claimed
WO-2012109586-A2 METHODS AND SYSTEMS FOR EVALUATING AND PREDICTING THE REACTIVITY OF MONOOXYGENASE ENZYMES UNIVERSITY OF ROCHESTER (US) 2012-08-16 WO claimed
CN-118922404-A Compound, polymerizable composition, cured product, color filter, partition wall, and image display device 三菱化学株式会社 2024-11-08 CN disclosed
CN-115210219-A Oxime ester photoinitiators 巴斯夫欧洲公司 2022-10-18 CN disclosed
CN-109803969-B 2-phenylphenoxy substituted perylene bisimide compounds and uses thereof 巴斯夫欧洲公司 2022-08-05 CN disclosed
US-9273342-B2 Methods and systems for evaluating and predicting the reactivity of monooxygenase enzymes UNIVERSITY OF ROCHESTER (US) 2016-03-01 US disclosed
US-20140038850-A1 METHODS AND SYSTEMS FOR EVALUATING AND PREDICTING THE REACTIVITY OF MONOOXYGENASE ENZYMES UNIVERSITY OF ROCHESTER (US) 2014-02-06 US disclosed
WO-2012109586-A2 METHODS AND SYSTEMS FOR EVALUATING AND PREDICTING THE REACTIVITY OF MONOOXYGENASE ENZYMES UNIVERSITY OF ROCHESTER (US) 2012-08-16 WO disclosed