Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 6/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1247800 | 0.93 | SCN9A (0.42) | SCN9ASCN5ANPSR1MAPTNTRK1 | |
| SCHEMBL1245138 | 0.92 | SCN9A (0.52) | SCN9ASCN5ANPSR1MAPTPPARG | |
| SCHEMBL1245272 | 0.88 | SCN9A (0.45) | SCN9ASCN5ANPSR1MAPTPPARG | |
| SCHEMBL3712293 | 0.87 | LPAR1 (0.49) | MAPTPPARGPPARDPPARANPC1 | |
| SCHEMBL1246481 | 0.84 | SCN9A (0.54) | SCN9ASCN5ANPSR1MAPTPPARD | |
| SCHEMBL11896062 | 0.83 | LPAR1 (0.47) | SCN9ASCN5ANPSR1MAPTALDH1A1 | |
| SCHEMBL1247570 | 0.83 | SCN9A (0.46) | SCN9ASCN5ANPSR1MAPTNTRK1 | |
| SCHEMBL1246308 | 0.82 | SCN9A (0.55) | SCN9ASCN5ANPSR1NTRK1TDP1 | |
| SCHEMBL1246915 | 0.82 | SCN9A (0.41) | SCN9ASCN5ANPSR1MAPTPPARG | |
| SCHEMBL9902692 | 0.82 | SCN9A (0.40) | SCN9ASCN5ANPSR1MAPTNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2462128-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | Amira Pharmaceuticals, Inc. (US) | 2012-06-13 | — | — | EP | claimed |
| WO-2011017350-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS, INC. (US) | 2011-02-10 | — | — | WO | claimed |