Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.43 |
| ▸ | ACACA | Q13085 | 3/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | GAK | O14976 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12475401 | 0.88 | ACACB (0.55) | ACACBACACAABL1 | |
| SCHEMBL12476070 | 0.88 | ACACB (0.44) | ACACBACACAPDGFRBPDGFRAABL1 | |
| SCHEMBL12476048 | 0.84 | ACACB (0.49) | ACACBACACAABL1 | |
| SCHEMBL12475857 | 0.75 | ACACB (0.46) | ACACBACACA | |
| SCHEMBL12475958 | 0.75 | ACACB (0.38) | ACACBACACAPDE4DPDE4APDE4B | |
| SCHEMBL12476251 | 0.74 | ACACB (0.43) | ACACBACACA | |
| SCHEMBL21772397 | 0.71 | SNCA (0.30) | — | |
| SCHEMBL5943172 | 0.70 | HAO1 (0.46) | ACACBACACAHIF1AKMT2A | |
| SCHEMBL5943020 | 0.69 | HAO1 (0.48) | ACACBACACAHIF1AKMT2A | |
| SCHEMBL12476390 | 0.69 | ACACB (0.46) | ACACBACACALNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012090219-A2 | THIAZOLE COMPOUNDS USEFUL AS ACETYL-COA CARBOXYLASE (ACC) INHIBITORS | JUBILANT BIOSYS LTD. (IN) | 2012-07-05 | — | — | WO | disclosed |