Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 8/20 | 0.86 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | F13A1 | P00488 | 1/20 | 0.62 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.58 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.58 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12001427 | 0.95 | ACACB (0.79) | ACACBSMN1; SMN2ALDH1A1NPC1MAPT | |
| SCHEMBL255805 | 0.93 | ACACB (1.00) | ACACBSMN1; SMN2ALDH1A1NPC1MAPT | |
| SCHEMBL4519919 | 0.87 | MAPT (0.67) | ACACBSMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL9259281 | 0.85 | ACACB (0.65) | ACACBSMN1; SMN2ALDH1A1KDM4EF13A1 | |
| SCHEMBL3726818 | 0.85 | ACACB (0.64) | ACACBSMN1; SMN2ALDH1A1NPC1MAPT | |
| SCHEMBL256313 | 0.84 | ACACB (0.66) | ACACBSMN1; SMN2ALDH1A1NPC1MAPT | |
| SCHEMBL10592850 | 0.84 | KDM4E (0.84) | ACACBSMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL12001375 | 0.83 | ACACB (0.80) | ACACBSMN1; SMN2ALDH1A1NPC1MAPT | |
| SCHEMBL659053 | 0.83 | SMN1; SMN2 (1.00) | ACACBSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL5726654 | 0.83 | ACACB (0.67) | ACACBSMN1; SMN2ALDH1A1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012090219-A2 | THIAZOLE COMPOUNDS USEFUL AS ACETYL-COA CARBOXYLASE (ACC) INHIBITORS | JUBILANT BIOSYS LTD. (IN) | 2012-07-05 | — | — | WO | disclosed |