Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | F13A1 | P00488 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375704 | 0.92 | ALDH1A1 (0.56) | ACACBSMN1; SMN2ALDH1A1KMT2AGAA | |
| SCHEMBL11200044 | 0.86 | GAA (0.56) | SMN1; SMN2KMT2AGAANPSR1 | |
| SCHEMBL3008925 | 0.86 | GAA (0.56) | SMN1; SMN2ALDH1A1GLAKMT2AGAA | |
| SCHEMBL12475741 | 0.85 | ACACB (0.86) | ACACBSMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL8835699 | 0.83 | GLA (0.55) | ACACBGLAKMT2AGAANPSR1 | |
| SCHEMBL12001427 | 0.81 | ACACB (0.79) | ACACBSMN1; SMN2ALDH1A1KDM4EF13A1 | |
| SCHEMBL11362199 | 0.81 | GAA (0.58) | ACACBSMN1; SMN2ALDH1A1GLAKMT2A | |
| SCHEMBL6375038 | 0.81 | CYP4F2 (0.66) | SMN1; SMN2ALDH1A1GAANPSR1KDM4E | |
| SCHEMBL7723659 | 0.80 | GAA (0.59) | SMN1; SMN2ALDH1A1GAANPSR1KDM4E | |
| SCHEMBL11817150 | 0.80 | PPARA (0.63) | ALDH1A1GAANPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407951-A | Anticoagulants, muscle relaxants, bronchodilators | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-18 | — | — | US | disclosed |
| US-5140038-A | Thromboxane A2 antagonists | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-18 | — | — | US | disclosed |
| US-4258058-A | Phenoxyalkylcarboxylic acid compounds and thrombocyte-aggregation inhibition | BOEHRINGER MANNHEIM GMBH (DE) | 1981-03-24 | — | — | US | disclosed |