Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 19/20 | 0.37 |
| ▸ | ACACA | Q13085 | 4/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17050447 | 0.92 | ACACB (0.41) | ACACBACACA | |
| SCHEMBL12476325 | 0.83 | ALDH1A1 (0.33) | ACACB | |
| SCHEMBL12475790 | 0.81 | ACACB (0.37) | ACACBACACACYP2C9CYP2C19 | |
| SCHEMBL12475981 | 0.81 | ACACB (0.44) | ACACBACACACYP2C9CYP2C19 | |
| SCHEMBL12475857 | 0.79 | ACACB (0.46) | ACACBACACACYP2C9CYP2C19 | |
| SCHEMBL1368651 | 0.77 | PTGS1 (0.32) | ACACBACACACYP2C9 | |
| SCHEMBL5942875 | 0.77 | ACACB (0.50) | ACACBACACACYP2C9CYP2C19 | |
| SCHEMBL12475997 | 0.77 | ACACB (0.57) | ACACBACACACYP2C9CYP2C19 | |
| SCHEMBL12476141 | 0.77 | ACACB (0.47) | ACACBACACA | |
| SCHEMBL12476283 | 0.73 | S1PR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012090219-A2 | THIAZOLE COMPOUNDS USEFUL AS ACETYL-COA CARBOXYLASE (ACC) INHIBITORS | JUBILANT BIOSYS LTD. (IN) | 2012-07-05 | — | — | WO | disclosed |