Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 16/20 | 0.64 |
| ▸ | NFKBIA | P25963 | 6/20 | 0.64 |
| ▸ | RELA | Q04206 | 6/20 | 0.64 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12474874 | 0.78 | SLC40A1 (0.67) | SLC40A1NFKBIARELA | |
| SCHEMBL11973725 | 0.78 | SLC40A1 (1.00) | SLC40A1NFKBIARELA | |
| SCHEMBL11973479 | 0.76 | SLC40A1 (1.00) | SLC40A1NFKBIARELAMMP2 | |
| SCHEMBL12474970 | 0.76 | SLC40A1 (0.63) | SLC40A1NFKBIARELAMMP2 | |
| SCHEMBL11973362 | 0.76 | SLC40A1 (1.00) | SLC40A1NFKBIARELA | |
| SCHEMBL414125 | 0.75 | SLC40A1 (1.00) | SLC40A1NFKBIARELAMMP2 | |
| SCHEMBL416275 | 0.71 | NFKBIA (1.00) | SLC40A1NFKBIARELAMMP2 | |
| SCHEMBL11973265 | 0.70 | SLC40A1 (1.00) | SLC40A1NFKBIARELA | |
| SCHEMBL11973718 | 0.69 | SLC40A1 (1.00) | SLC40A1NFKBIARELA | |
| SCHEMBL12475870 | 0.69 | SLC40A1 (0.61) | SLC40A1NFKBIARELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675526-A1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | Vifor (International) AG (CH) | 2013-12-25 | — | — | EP | disclosed |
| WO-2012110603-A1 | NOVEL SULFONAMINOQUINOLINE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2012-08-23 | — | — | WO | disclosed |