Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.56 |
| ▸ | HK1 | P19367 | 1/20 | 0.54 |
| ▸ | HK2 | P52789 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14120235 | 1.00 | TYR (0.56) | TYRHK1HK2 | |
| SCHEMBL12476682 | 1.00 | TYR (0.56) | TYRHK1HK2 | |
| SCHEMBL20056340 | 0.90 | TYR (0.55) | TYR | |
| SCHEMBL14119799 | 0.90 | TYR (0.55) | TYR | |
| SCHEMBL1661003 | 0.90 | TYR (0.60) | TYR | |
| SCHEMBL14120256 | 0.90 | TYR (0.60) | TYR | |
| SCHEMBL1660999 | 0.90 | TYR (0.60) | TYR | |
| SCHEMBL16843515 | 0.89 | — | — | |
| SCHEMBL13553204 | 0.89 | — | — | |
| SCHEMBL15040924 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10273260-B2 | Compounds and methods for treating bacterial infections | WASHINGTON UNIVERSITY (US) | 2019-04-30 | — | — | US | disclosed |
| EP-2672820-B1 | MANNOSIDE COMPOUNDS AND METHODS OF USE THEREOF | UNIV WASHINGTON (US) | 2019-04-17 | — | — | EP | disclosed |
| US-20170247401-A1 | COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS | WASHINGTON UNIVERSITY | 2017-08-31 | — | — | US | disclosed |
| US-9567362-B2 | Compounds and methods for treating bacterial infections | WASHINGTON UNIVERSITY (US) | 2017-02-14 | — | — | US | disclosed |
| US-20150197538-A1 | COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-07-16 | — | — | US | disclosed |
| US-8937167-B2 | Compounds and methods for treating bacterial infections | WASHINGTON UNIVERSITY (US) | 2015-01-20 | — | — | US | disclosed |
| EP-2672820-A1 | MANNOSIDE COMPOUNDS AND METHODS OF USE THEREOF | The Washington University (US) | 2013-12-18 | — | — | EP | disclosed |
| US-20120309701-A1 | COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS | THE WASHINGTON UNIVERSITY (US) | 2012-12-06 | — | — | US | disclosed |
| WO-2012109263-A1 | MANNOSIDE COMPOUNDS AND METHODS OF USE THEREOF | THE WASHINGTON UNIVERSITY (US) | 2012-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10273260-B2 | Compounds and methods for treating bacterial infections | MMP8, ELANE, GUSB | TYR 270/4885HK1 603/4885HK2 527/4885 |
| US-20120309701-A1 | COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS | MMP8, ELANE, GUSB | TYR 270/4885HK1 603/4885HK2 527/4885 |
| US-20170247401-A1 | COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS | MMP8, ELANE, GUSB | TYR 270/4885HK1 603/4885HK2 527/4885 |
| US-20150197538-A1 | COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS | MMP8, ELANE, GUSB | TYR 270/4885HK1 603/4885HK2 527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.