SCHEMBL1247669

SCHEMBL1247669

N#Cc1ccc2[nH]c3ccccc3c2c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHUK O15111 1/20 0.63
AR P10275 1/20 0.61
AHR P35869 1/20 0.57
GABRP O00591 1/20 0.57
GABRD O14764 1/20 0.57
GABRA1 P14867 1/20 0.57
GABRB1 P18505 1/20 0.57
GABRG2 P18507 1/20 0.57
GABRB3 P28472 1/20 0.57
GABRA5 P31644 1/20 0.57
GABRA3 P34903 1/20 0.57
GABRA2 P47869 1/20 0.57
GABRB2 P47870 1/20 0.57
GABRA4 P48169 1/20 0.57
GABRE P78334 1/20 0.57
GABRA6 Q16445 1/20 0.57
GABRG1 Q8N1C3 1/20 0.57
GABRG3 Q99928 1/20 0.57
GABRQ Q9UN88 1/20 0.57
ALDH1A1 P00352 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30480932 1.00 CHUK (0.63) CHUKARAHRGABRPGABRD
SCHEMBL31272617 1.00 CHUK (0.63) CHUKARAHRGABRPGABRD
SCHEMBL31273378 1.00 CHUK (0.63) CHUKARAHRGABRPGABRD
Hydrochloric Acid SCHEMBL27851102 0.98 CHUK (0.61) CHUKARAHRGABRPGABRD
SCHEMBL31139500 0.93 CHUK (0.56) CHUKARAHRGABRPGABRD
SCHEMBL29402283 0.90 CHUK (0.68) CHUKARMEN1KMT2AFASN
SCHEMBL606784 0.90 CHUK (0.68) CHUKARMEN1KMT2AFASN
SCHEMBL30545930 0.90 CHUK (0.68) CHUKARMEN1KMT2AFASN
SCHEMBL6009650 0.89 KIF11 (0.58) CHUKARAHRGABRPGABRD
SCHEMBL30414171 0.89 KIF11 (0.58) CHUKARAHRGABRPGABRD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 405 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118047715-A Benzoyl carbazole derivative and application thereof in phosphorescent material 三峡大学 2024-05-17 CN claimed
CN-118047753-A Pyrrolecarboxyl carbazole derivatives and their use in phosphorescent materials 三峡大学 2024-05-17 CN claimed
CN-114058306-B Underfill adhesive, and preparation method and application thereof 韦尔通科技股份有限公司 2023-07-21 CN claimed
CN-114058306-A Underfill adhesive and preparation method and application thereof 韦尔通(厦门)科技股份有限公司 2022-02-18 CN claimed
EP-3698788-A1 COMPOSITION COMPRISING TETRACYCLIC COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2020-08-26 EP claimed
EP-2606886-B1 COMPOSITION COMPRISING TETRACYCLIC COMPOUND CHUGAI PHARMACEUTICAL CO LTD (JP) 2020-01-08 EP claimed
CN-110590739-A Preparation method of erlotinib 中国药科大学 2019-12-20 CN claimed
CN-110357889-A Protein degradation target compound, its antitumor application thereof, wherein mesosome and intermediate application 上海科技大学 2019-10-22 CN claimed
CN-107033125-B A kind of Ai Le replaces the preparation method of Buddhist nun 湖南博奥德药业有限公司 2019-09-20 CN claimed
CN-106928185-B A kind of Ai Le replaces the preparation method of Buddhist nun 湖南博奥德药业有限公司 2019-09-20 CN claimed
CN-107033125-A A kind of Ai Le replaces the preparation method of Buddhist nun 湖南博奥德生物医药技术开发有限公司 2017-08-11 CN claimed
CN-106995433-A A kind of Ai Le replaces the preparation method of Buddhist nun 湖南博奥德生物医药技术开发有限公司 2017-08-01 CN claimed
CN-106928185-A A kind of Ai Le replaces the preparation method of Buddhist nun 湖南博奥德生物医药技术开发有限公司 2017-07-07 CN claimed
CN-106518842-A Alectinib preparation method 北京万全德众医药生物技术有限公司 2017-03-22 CN claimed
CN-106456556-A Novel pharmaceutical compositions comprising nonionic surfactants 豪夫迈·罗氏有限公司 2017-02-22 CN claimed
CN-105777710-A Synthesis method of Alectinib 湖南欧亚生物有限公司 2016-07-20 CN claimed
CN-103052386-B Compositions containing tetracyclic compound CHUGAI PHARMACEUTICAL CO.,LTD. (JP) 2016-03-02 CN claimed
CN-102459172-B Tetracyclic compound CHUGAI PHARMACEUTICAL CO LTD 2015-06-24 CN claimed
CN-103052386-A Composition containing tetracyclic compound CHUGAI PHARMACEUTICAL CO LTD 2013-04-17 CN claimed
CN-102459172-A Tetracyclic compounds CHUGAI PHARMACEUTICAL CO LTD 2012-05-16 CN claimed