Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.37 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12477406 | 0.90 | PTGER2 (0.36) | HDAC3HDAC1HDAC2HDAC6PTGER2 | |
| SCHEMBL12476945 | 0.83 | PTPN1 (0.41) | HDAC3HDAC1HDAC2HDAC6PTPN1 | |
| SCHEMBL12476661 | 0.81 | CNR2 (0.39) | DPP4 | |
| SCHEMBL12477484 | 0.80 | S1PR1 (0.56) | HDAC3HDAC1HDAC2HDAC6DEGS1 | |
| SCHEMBL15329798 | 0.80 | S1PR1 (0.56) | HDAC3HDAC1HDAC2HDAC6DEGS1 | |
| SCHEMBL12477191 | 0.79 | PPARG (0.47) | HDAC3HDAC1HDAC2HDAC6DEGS1 | |
| SCHEMBL12477187 | 0.79 | PPARG (0.47) | HDAC3HDAC1HDAC2HDAC6DEGS1 | |
| SCHEMBL12477019 | 0.79 | FFAR1 (0.41) | S1PR1IDO1FFAR1PPARGPPARD | |
| SCHEMBL12476657 | 0.78 | PPARA (0.41) | HDAC3HDAC1HDAC2HDAC6PTGER2 | |
| SCHEMBL16914905 | 0.78 | PPARD (0.54) | PTPN1FFAR1PTPN2PTPN6PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2658851-A1 | HETEROCYCLIC COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA | Cadila Healthcare Limited (IN) | 2013-11-06 | — | — | EP | disclosed |
| WO-2012090220-A1 | HETEROCYCLIC COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA | CADILA HEALTHCARE LIMITED (IN) | 2012-07-05 | — | — | WO | disclosed |