Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12476644 | 0.90 | FFAR1 (0.40) | FFAR1FFAR4PPARAPPARDPPARG | |
| SCHEMBL12476945 | 0.80 | PTPN1 (0.41) | PPARAPPARDPPARGMAOB | |
| SCHEMBL12476718 | 0.80 | RORC (0.38) | — | |
| SCHEMBL4726499 | 0.79 | PSEN1 (0.46) | PPARAPPARDPPARGS1PR1IDO1 | |
| SCHEMBL12477486 | 0.79 | HDAC3 (0.38) | FFAR1PPARAPPARDPPARGS1PR1 | |
| SCHEMBL12477015 | 0.78 | S1PR1 (0.58) | FFAR1FFAR4PPARAPPARDPPARG | |
| SCHEMBL12477210 | 0.78 | S1PR1 (0.58) | FFAR1FFAR4PPARAPPARDPPARG | |
| SCHEMBL16914905 | 0.77 | PPARD (0.54) | FFAR1PPARAPPARDPPARGMAOB | |
| SCHEMBL16915039 | 0.77 | ADAMTS4 (0.37) | FFAR1FFAR4PPARAPPARDPPARG | |
| SCHEMBL12477207 | 0.77 | S1PR1 (0.47) | FFAR1FFAR4PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2658851-A1 | HETEROCYCLIC COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA | Cadila Healthcare Limited (IN) | 2013-11-06 | — | — | EP | claimed |
| WO-2012090220-A1 | HETEROCYCLIC COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA | CADILA HEALTHCARE LIMITED (IN) | 2012-07-05 | — | — | WO | claimed |