⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13174225 | 0.96 | INMT (0.33) | — | |
| SCHEMBL7208434 | 0.96 | INMT (0.33) | — | |
| SCHEMBL13174086 | 0.96 | INMT (0.33) | — | |
| SCHEMBL12039647 | 0.96 | INMT (0.33) | — | |
| SCHEMBL2184351 | 0.87 | — | — | |
| SCHEMBL15094238 | 0.87 | INMT (0.30) | — | |
| SCHEMBL24681421 | 0.85 | — | — | |
| SCHEMBL28550749 | 0.85 | — | — | |
| SCHEMBL17530849 | 0.83 | CA12 (0.35) | — | |
| SCHEMBL24962137 | 0.81 | CYP1A2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3624 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515627-A | Continuous synthesis method of deuterated heterocyclic compound and catalyst fixed bed system | 安徽泽升科技股份有限公司 | 2024-08-20 | — | — | CN | claimed |
| US-20230146395-A1 | Substituted Pyrimidines and Uses Thereof | Verge Analytics, Inc. (US) | 2023-05-11 | — | — | US | claimed |
| EP-4118087-A1 | SUBSTITUTED FURO[3,2-D]PYRIMIDINES AND USES THEREOF | Verge Analytics, Inc. (US) | 2023-01-18 | — | — | EP | claimed |
| WO-2022261068-A1 | METHODS AND TREATMENT OF VIRAL INFECTION WITH SUBSTITUTED FURO-PYRIMIDINES | Verge Analytics, Inc. (US) | 2022-12-15 | — | — | WO | claimed |
| WO-2021183439-A1 | SUBSTITUTED FURO[3,2-D]PYRIMIDINES AND USES THEREOF | Verge Analytics, Inc. (US) | 2021-09-16 | — | — | WO | claimed |
| CN-111718332-B | 2-substituted pyrazol amino-4-substituted amino-5-pyrimidine formamide compound, composition and application thereof | 北京赛特明强医药科技有限公司 | 2021-08-17 | — | — | CN | claimed |
| CN-111718332-A | 2-substituted pyrazol amino-4-substituted amino-5-pyrimidine formamide compound, composition and application thereof | 北京赛特明强医药科技有限公司 | 2020-09-29 | — | — | CN | claimed |
| US-10201525-B2 | Tetrazole-substituted arylamides as PX2 and PX2/3 antagonists | ROCHE PALO ALTO LLC (US) | 2019-02-12 | — | — | US | claimed |
| EP-2976339-B1 | GEMINALLY SUBSTITUTED CYANOETHYLPYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2018-06-27 | — | — | EP | claimed |
| US-9957264-B2 | Geminally substituted cyanoethylpyrazolo pyridones as Janus kinase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2018-05-01 | — | — | US | claimed |
| EP-0604368-A1 | Anti retroviral hydrazine derivatives | CIBA-GEIGY AG (CH) | 1994-06-29 | — | — | EP | claimed |
| US-5312459-A | Nitrogen additives to fuel | SPRUGEL FRIEDRICH A | 1994-05-17 | — | — | US | claimed |
| EP-0594540-A1 | Antiretroviral acyl compounds | CIBA-GEIGY AG (CH) | 1994-04-27 | — | — | EP | claimed |
| WO-1992022545-A1 | NEW COUMARIN DERIVATIVES | FIDIA S.P.A. (IT) | 1992-12-23 | — | — | WO | claimed |
| EP-0410202-B1 | ADDITIVE FOR LIQUIFIEDGAS-FUEL | Sprügel, Friedrich (DE) | 1992-09-30 | — | — | EP | claimed |
| US-5028693-A | Preparation of polypeptides, fewer by-products | BIORESEARCH, INC. (US) | 1991-07-02 | — | — | US | claimed |
| EP-0410202-A1 | Additive for liquifiedgas-fuel | Sprügel, Friedrich (DE) | 1991-01-30 | — | — | EP | claimed |
| EP-0401093-A1 | Pyrrolidone derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1990-12-05 | — | — | EP | claimed |
| EP-0385038-A1 | Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them | The Boots Company PLC (GB) | 1990-09-05 | — | — | EP | claimed |
| US-4016263-A | BACTERICIDES | BOEHRINGER INGELHEIM GMBH (DT) | 1977-04-05 | — | — | US | claimed |