Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29829450 | 0.89 | SLC17A5 (0.54) | SLC17A5KDM4EALDH1A1HPGDGLA | |
| SCHEMBL29804846 | 0.89 | SLC17A5 (0.54) | SLC17A5KDM4EALDH1A1HPGDGLA | |
| SCHEMBL29829025 | 0.85 | SLC17A5 (0.55) | SLC17A5KDM4EALDH1A1HPGDGLA | |
| SCHEMBL22702156 | 0.81 | TLR2 (0.57) | SLC17A5KMT2ATLR2CASP3 | |
| SCHEMBL28686934 | 0.81 | TLR2 (0.57) | SLC17A5KMT2ATLR2CASP3 | |
| SCHEMBL31369887 | 0.79 | TLR2 (0.53) | SLC17A5KMT2ATLR2CASP3 | |
| SCHEMBL31370150 | 0.79 | TLR2 (0.53) | SLC17A5TLR2CASP3 | |
| SCHEMBL15374822 | 0.79 | ALDH1A1 (0.70) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL31369789 | 0.79 | FOLH1 (0.54) | SLC17A5POLBTLR2CASP3 | |
| SCHEMBL31369717 | 0.79 | EPHX2 (0.52) | SLC17A5KMT2AMEN1TLR2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011089257-A1 | METHOD FOR DETERMINING THE ACTIVITY OF TRANSGLUTAMINASE FACTOR XIIIA | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2011-07-28 | — | — | WO | disclosed |
| EP-2348038-A1 | Method for determining the activity of transglutaminase factor XIIIa | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2011-07-27 | — | — | EP | disclosed |