Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10761456 | 0.93 | TSHR (0.45) | TSHRPOLBALDH1A1KDM4EHPGD | |
| SCHEMBL9778744 | 0.83 | CHRNB4 (0.38) | POLBALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9778471 | 0.81 | KCNH2 (0.47) | — | |
| SCHEMBL9778992 | 0.79 | KDM1A (0.46) | ALDH1A1HPGDGAASMN1; SMN2NPC1 | |
| SCHEMBL13558669 | 0.79 | SMN1; SMN2 (0.51) | TSHRPOLBALDH1A3KMT2AMEN1 | |
| SCHEMBL9451018 | 0.78 | MEN1 (0.41) | TSHRPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL29281398 | 0.76 | HPGD (0.52) | POLBALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL29950610 | 0.76 | KDM1A (0.46) | ALDH1A1HPGDGAASMN1; SMN2NPC1 | |
| SCHEMBL11978140 | 0.75 | NQO1 (0.50) | TSHRALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11957485 | 0.75 | SLC6A2 (0.36) | TSHRALDH1A1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348096-A2 | Synthesis of hybrid block copolymers and uses thereof | Intezyne Technologies Inc. (US) | 2011-07-27 | — | — | EP | disclosed |