SCHEMBL9778992

SCHEMBL9778992

COc1ccc(C2OCCCO2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.46
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
HPGD P15428 2/20 0.43
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
GAA P10253 1/20 0.41
ALDH1A1 P00352 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
DRD2 P14416 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
SLC6A3 Q01959 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29950610 0.96 KDM1A (0.46) KDM1AMAOAMAOBCA12CA1
SCHEMBL4723773 0.92 MAOA (0.48) KDM1AMAOAMAOBCA12CA1
SCHEMBL9779134 0.90 KDM4E (0.45) HPGDMAPTGAASMN1; SMN2
SCHEMBL8155961 0.86 ESR2 (0.45) KDM1AMAOAMAOBCA12CA1
SCHEMBL9778813 0.86 APP (0.51) MAOBHPGDMAPTALDH1A1SMN1; SMN2
SCHEMBL19221186 0.83 MAOA (0.48) KDM1AMAOAMAOBCA12CA1
SCHEMBL9451018 0.82 MEN1 (0.41) LMNAMAPTALDH1A1SMN1; SMN2NPC1
SCHEMBL31165268 0.82 MAPT (0.59) KDM1AMAOAMAOBHPGDLMNA
SCHEMBL9778655 0.82 KDM4E (0.44) KDM1AMAOAMAOBMAPTGAA
SCHEMBL11384551 0.80 KDM1A (0.46) KDM1AMAOAMAOBCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025035152-A2 THERMOSET MATERIALS AND METHODS OF MAKING AND USING SAME CORNELL UNIVERSITY (US) 2025-02-13 WO disclosed
EP-2137193-B1 SUBSTITUTED DIHYDRO AND TETRAHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF SANOFI SA (FR) 2017-08-09 EP disclosed
US-20150232616-A1 HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS INTEZYNE TECHNOLOGIES, INC. 2015-08-20 US disclosed
US-8980326-B2 Hybrid block copolymer micelles with mixed stereochemistry for encapsulation of hydrophobic agents INTEZYNE TECHNOLOGIES, INC. (US) 2015-03-17 US disclosed
US-8779008-B2 Polymeric micelles for drug delivery INTEZYNE TECHNOLOGIES, INC. (US) 2014-07-15 US disclosed
US-20130195987-A1 POLYMERIC MICELLES FOR DRUG DELIVERY INTEZYNE TECHNOLOGIES, INC. (US) 2013-08-01 US disclosed
US-20130196987-A1 MACROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS EISAI CO., LTD. (JP) 2013-08-01 US disclosed
US-20130196987-A1 MACROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS EISAI CO., LTD. (JP) 2013-08-01 US disclosed
US-8426477-B1 Polymeric micelles for drug delivery INTEZYNE TECHNOLOGIES, LLC (US) 2013-04-23 US disclosed
US-8329742-B2 Macrocyclic compounds useful as pharmaceuticals EISAI CO., LTD. (JP) 2012-12-11 US disclosed
US-20110021718-A1 SYNTHESIS OF HYBRID BLOCK COPOLYMERS AND USES THEREOF INTEZYNE TECHNOLOGIES (US) 2011-01-27 US disclosed
US-7799827-B2 Macrocyclic compounds useful as pharmaceuticals EISAI CO., LTD. (JP) 2010-09-21 US disclosed
US-7799827-B2 Macrocyclic compounds useful as pharmaceuticals EISAI CO., LTD. (JP) 2010-09-21 US disclosed
US-5063197-A Aromatic compound MITSUBISHI PAPER MILLS LIMITED (JP) 1991-11-05 US disclosed
EP-0309248-A2 Acrylated diols MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-03-29 EP disclosed
EP-0031566-B1 PHOTOSENSITIVE NEGATIVE-WORKING TONABLE ELEMENT E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-03-14 EP disclosed
US-4356252-A POLYMERIC BINDER, PHOTOINITIATOR, ACETAL, PLASTICIZING, POLYMERIC ANHYDRIDE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-10-26 US disclosed
US-4294909-A Photosensitive negative-working toning process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-10-13 US disclosed
US-4292394-A Process for preparing multicolor toned images on a single photosensitive layer E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-09-29 US disclosed
EP-0031566-A1 Photosensitive negative-working tonable element E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-07-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130195987-A1 POLYMERIC MICELLES FOR DRUG DELIVERY ABCB4, CLTB, CD47 KDM1A 4255/4885MAOA 3781/4885MAOB 3383/4885
US-20130196987-A1 MACROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS FLT4, VEGFA, FLT1 KDM1A 4558/4885MAOA 2106/4885MAOB 1695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.