Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.63 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.58 |
| ▸ | GALR2 | O43603 | 8/20 | 0.55 |
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12486733 | 0.99 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL12485635 | 0.99 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL12484612 | 0.97 | MEN1 (0.59) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL12486690 | 0.89 | AURKA (0.65) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL12485812 | 0.89 | MAPT (0.64) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL12486039 | 0.88 | MAPT (0.67) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL12486589 | 0.88 | BPTF (0.54) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL20042146 | 0.87 | MAPT (0.65) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL12486475 | 0.87 | SLC2A1 (0.49) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL12485669 | 0.86 | MEN1 (0.49) | MEN1KMT2AALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890138-B2 | Diaminopyrimidine derivatives and processes for the preparation thereof | YUHAN CORPORATION (KR) | 2018-02-13 | — | — | US | claimed |
| EP-2678332-B1 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2016-05-18 | — | — | EP | claimed |
| US-20150274700-A2 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2015-10-01 | — | — | US | claimed |
| CN-103402997-B | Diaminopyrimidine derivatives and process for preparing same | Liu Hanyangxing (KR) | 2015-08-26 | — | — | CN | claimed |
| EP-2678332-A2 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 2014-01-01 | — | — | EP | claimed |
| US-20130338179-A1 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2013-12-19 | — | — | US | claimed |
| CN-103402997-A | Diaminopyrimidine derivatives and process for preparing same | YUHAN INC | 2013-11-20 | — | — | CN | claimed |
| WO-2012115480-A2 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2012-08-30 | — | — | WO | claimed |
| US-10227330-B2 | Diaminopyrimidine derivatives and processes for the preparation thereof | YUHAN CORPORATION (KR) | 2019-03-12 | — | — | US | disclosed |
| US-20180111918-A1 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2018-04-26 | — | — | US | disclosed |
| US-9890138-B2 | Diaminopyrimidine derivatives and processes for the preparation thereof | YUHAN CORPORATION (KR) | 2018-02-13 | — | — | US | disclosed |
| EP-2678332-B1 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2016-05-18 | — | — | EP | disclosed |
| US-20150274700-A2 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2015-10-01 | — | — | US | disclosed |
| CN-103402997-B | Diaminopyrimidine derivatives and process for preparing same | Liu Hanyangxing (KR) | 2015-08-26 | — | — | CN | disclosed |
| EP-2678332-A2 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 2014-01-01 | — | — | EP | disclosed |
| US-20130338179-A1 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2013-12-19 | — | — | US | disclosed |
| CN-103402997-A | Diaminopyrimidine derivatives and process for preparing same | YUHAN INC | 2013-11-20 | — | — | CN | disclosed |
| WO-2012115480-A2 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2012-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274700-A2 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | HRH2, GIPR, SSTR4 | MEN1 4759/4885KMT2A 4017/4885ALDH1A1 3199/4885 |
| US-20130338179-A1 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | HRH2, GIPR, SSTR4 | MEN1 4759/4885KMT2A 4017/4885ALDH1A1 3199/4885 |
| US-20180111918-A1 | DIAMINOPYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | HRH2, GIPR, SSTR4 | MEN1 4759/4885KMT2A 4017/4885ALDH1A1 3199/4885 |
| US-10227330-B2 | Diaminopyrimidine derivatives and processes for the preparation thereof | HRH2, GIPR, SSTR4 | MEN1 4759/4885KMT2A 4017/4885ALDH1A1 3199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.