Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL901091 | 0.82 | HSD17B10 (0.59) | HSD17B10PARP1ALDH1A1CES2BCHE | |
| SCHEMBL15477049 | 0.81 | HSD17B10 (0.43) | HSD17B10PARP1ALDH1A1CES2BCHE | |
| SCHEMBL15477048 | 0.81 | HSD17B10 (0.43) | HSD17B10PARP1ALDH1A1CES2BCHE | |
| SCHEMBL546727 | 0.81 | HSD17B10 (0.40) | HSD17B10PARP1ALDH1A1CES2BCHE | |
| SCHEMBL547828 | 0.80 | ALDH1A1 (0.54) | HSD17B10PARP1ALDH1A1CES2BCHE | |
| SCHEMBL548323 | 0.75 | MEN1 (0.34) | HSD17B10CES1MEN1KMT2AUNG | |
| SCHEMBL546728 | 0.73 | HSD17B10 (0.50) | HSD17B10ALDH1A1L3MBTL1RXFP1MEN1 | |
| SCHEMBL9390822 | 0.73 | HSD17B10 (0.42) | HSD17B10ALDH1A1CES2BCHECES1 | |
| SCHEMBL21831060 | 0.72 | PARP1 (0.45) | HSD17B10PARP1ALDH1A1CES2BCHE | |
| SCHEMBL28813379 | 0.71 | HSD17B10 (0.47) | HSD17B10ALDH1A1CES2BCHECES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790484-B2 | Silica encapsulated biomaterials | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2017-10-17 | — | — | US | disclosed |
| US-20140051144-A1 | SILICA ENCAPSULATED BIOMATERIALS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2014-02-20 | — | — | US | disclosed |
| WO-2012116013-A2 | SILICA ENCAPSULATED BIOMATERIALS | WACKETT LAWRENCE P (US) | 2012-08-30 | — | — | WO | disclosed |