SCHEMBL12486208

SCHEMBL12486208

Oc1c(O)c2cc3ccccc3c3ccc4cccc1c4c23

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.63
FYN P06241 2/20 0.63
ACHE P22303 2/20 0.63
AHR P35869 2/20 0.63
ERBB2 P04626 1/20 0.63
MAOA P21397 1/20 0.63
ALDH1A1 P00352 8/20 0.54
HSD17B10 Q99714 6/20 0.54
HPGD P15428 5/20 0.54
THRB P10828 1/20 0.54
HIF1A Q16665 2/20 0.48
CYP1B1 Q16678 1/20 0.48
TSHR P16473 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
MAPK1 P28482 1/20 0.44
CASP1 P29466 1/20 0.44
TRPM4 Q8TD43 1/20 0.44
HPRT1 P00492 1/20 0.41
MAPT P10636 2/20 0.40
PTPN22 Q9Y2R2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL55922 0.84 CYP1A2 (0.73) CYP1A2FYNACHEAHRERBB2
SCHEMBL29731903 0.84 CYP1A2 (0.73) CYP1A2FYNACHEAHRERBB2
SCHEMBL132623 0.84 CYP1A2 (0.73) CYP1A2FYNACHEAHRERBB2
SCHEMBL4855410 0.82 CYP1A2 (0.70) CYP1A2FYNACHEAHRERBB2
SCHEMBL4848683 0.82 CYP1A2 (0.70) CYP1A2FYNACHEAHRERBB2
SCHEMBL4847142 0.82 CYP1A2 (0.70) CYP1A2FYNACHEAHRERBB2
SCHEMBL2935017 0.82 ALDH1A1 (0.62) CYP1A2FYNACHEAHRERBB2
SCHEMBL31035972 0.82 ALDH1A1 (0.62) CYP1A2FYNACHEAHRERBB2
SCHEMBL4847662 0.81 CYP1A2 (0.68) CYP1A2FYNACHEAHRERBB2
SCHEMBL4852478 0.80 CYP1A2 (0.96) CYP1A2FYNACHEAHRERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9790484-B2 Silica encapsulated biomaterials REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2017-10-17 US disclosed
US-20140051144-A1 SILICA ENCAPSULATED BIOMATERIALS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2014-02-20 US disclosed
WO-2012116013-A2 SILICA ENCAPSULATED BIOMATERIALS WACKETT LAWRENCE P (US) 2012-08-30 WO disclosed