Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | G6PD | P11413 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30991604 | 0.80 | KDM4E (0.53) | HPGDKDM4EALDH1A1CA12CA1 | |
| SCHEMBL3391576 | 0.80 | HPGD (0.58) | HPGDKDM4EALDH1A1CA12CA1 | |
| SCHEMBL27778819 | 0.80 | KDM4E (0.53) | HPGDKDM4EALDH1A1CA12CA1 | |
| SCHEMBL20349104 | 0.78 | NR4A1 (0.53) | HPGDKDM4EALDH1A1CA12CA1 | |
| SCHEMBL9154691 | 0.78 | NR4A1 (0.53) | HPGDKDM4EALDH1A1CA12CA1 | |
| SCHEMBL3389128 | 0.78 | HPGD (0.61) | HPGDKDM4EALDH1A1CA12CA1 | |
| SCHEMBL29940636 | 0.78 | HSD17B10 (0.67) | HPGDKDM4EALDH1A1CA12CA1 | |
| SCHEMBL689259 | 0.78 | HSD17B10 (0.67) | HPGDKDM4EALDH1A1CA12CA1 | |
| SCHEMBL28539627 | 0.77 | NR4A1 (0.61) | HPGDKDM4EALDH1A1CA12CA1 | |
| SCHEMBL3391137 | 0.76 | HPGD (0.58) | HPGDKDM4EALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790484-B2 | Silica encapsulated biomaterials | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2017-10-17 | — | — | US | disclosed |
| CN-103917098-A | Silica encapsulated biomaterials | UNIV MINNESOTA | 2014-07-09 | — | — | CN | disclosed |
| US-20140051144-A1 | SILICA ENCAPSULATED BIOMATERIALS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2014-02-20 | — | — | US | disclosed |
| WO-2012116013-A2 | SILICA ENCAPSULATED BIOMATERIALS | WACKETT LAWRENCE P (US) | 2012-08-30 | — | — | WO | disclosed |