SCHEMBL12486294

SCHEMBL12486294

O=C(O)C(=O)/C=C\c1ccc2ccccc2c1O

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1B1 Q16678 8/20 0.51
CYP1A1 P04798 5/20 0.51
ABCG2 Q9UNQ0 3/20 0.50
LDHA P00338 1/20 0.49
MAOB P27338 1/20 0.46
PTPN22 Q9Y2R2 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15477236 1.00 CYP1B1 (0.51) CYP1B1CYP1A1ABCG2LDHAMAOB
SCHEMBL21060616 1.00 CYP1B1 (0.51) CYP1B1CYP1A1ABCG2LDHAMAOB
SCHEMBL765995 0.87 CYP1B1 (0.54) CYP1B1CYP1A1ABCG2LDHAMAOB
SCHEMBL765996 0.87 CYP1B1 (0.54) CYP1B1CYP1A1ABCG2LDHAMAOB
SCHEMBL12484665 0.86 CYP1B1 (0.39) CYP1B1CYP1A1ABCG2MAOB
SCHEMBL12484669 0.86 CYP1B1 (0.39) CYP1B1CYP1A1ABCG2MAOB
SCHEMBL15476964 0.83 KDM4E (0.47) CYP1B1CYP1A1ABCG2LDHAMAOB
SCHEMBL15476962 0.83 KDM4E (0.47) CYP1B1CYP1A1ABCG2LDHAMAOB
SCHEMBL21060618 0.79 CYP1A1 (0.54) CYP1B1CYP1A1ABCG2HDAC8
SCHEMBL8423542 0.76 CYP1B1 (0.55) CYP1B1CYP1A1ABCG2LDHAPTPN22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11060079-B2 Methods and microorganisms for producing flavors and fragrance chemicals ARDRA INC. (CA) 2021-07-13 US disclosed
US-20190177713-A1 METHODS AND MICROORGANISMS FOR PRODUCING FLAVORS AND FRAGRANCE CHEMICALS ARDRA INC. (CA) 2019-06-13 US disclosed
US-9790484-B2 Silica encapsulated biomaterials REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2017-10-17 US disclosed
US-20140051144-A1 SILICA ENCAPSULATED BIOMATERIALS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2014-02-20 US disclosed
WO-2012116013-A2 SILICA ENCAPSULATED BIOMATERIALS WACKETT LAWRENCE P (US) 2012-08-30 WO disclosed