Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGFR | P43088 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12484665 | 1.00 | CYP1B1 (0.39) | CYP1B1CYP1A1MAOBTBXA2RPTGER4 | |
| SCHEMBL12486294 | 0.86 | CYP1B1 (0.51) | CYP1B1CYP1A1MAOBABCG2 | |
| SCHEMBL21060616 | 0.86 | CYP1B1 (0.51) | CYP1B1CYP1A1MAOBABCG2 | |
| SCHEMBL15477236 | 0.86 | CYP1B1 (0.51) | CYP1B1CYP1A1MAOBABCG2 | |
| SCHEMBL12486807 | 0.76 | NFKB1 (0.44) | MAOBTBXA2RPTGER4PTGFRPTGER3 | |
| SCHEMBL12486811 | 0.76 | NFKB1 (0.44) | MAOBTBXA2RPTGER4PTGFRPTGER3 | |
| SCHEMBL12485801 | 0.74 | KMT2A (0.41) | CYP1B1CYP1A1MAOBKDM4EALDH1A1 | |
| SCHEMBL15477027 | 0.74 | KMT2A (0.41) | CYP1B1CYP1A1MAOBKDM4EALDH1A1 | |
| SCHEMBL765996 | 0.73 | CYP1B1 (0.54) | CYP1B1CYP1A1MAOBTBXA2RPTGER4 | |
| SCHEMBL765995 | 0.73 | CYP1B1 (0.54) | CYP1B1CYP1A1MAOBTBXA2RPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790484-B2 | Silica encapsulated biomaterials | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2017-10-17 | — | — | US | disclosed |
| US-20140051144-A1 | SILICA ENCAPSULATED BIOMATERIALS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2014-02-20 | — | — | US | disclosed |
| WO-2012116013-A2 | SILICA ENCAPSULATED BIOMATERIALS | WACKETT LAWRENCE P (US) | 2012-08-30 | — | — | WO | disclosed |