SCHEMBL12487461

SCHEMBL12487461

Nc1cc(Nc2ccc3nnn(Cc4ccc5ncccc5c4)c3n2)ccn1

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MET P08581 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12489342 0.88 MET (0.57) MET
SCHEMBL12489535 0.88 MET (0.59) MET
SCHEMBL1329155 0.87 MET (0.60) MET
SCHEMBL12693342 0.87 MET (0.53) MET
SCHEMBL12486149 0.86 MET (0.52) MET
SCHEMBL12489343 0.84 MET (0.60) MET
SCHEMBL12489734 0.81 MET (0.64) MET
SCHEMBL12486145 0.81 MET (0.53) MET
SCHEMBL20499791 0.81 MET (0.56) MET
SCHEMBL13468987 0.80 MET (0.51) MET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011079804-A1 CERTAIN TRIAZOLOPYRIDINES AND TRIAZOLOPYRAZINES, COMPOSITIONS THEREOF AND METHODS OF USE THEREFOR HUTCHISON MEDIPHARMA LIMITED (CN) 2011-07-07 WO disclosed