Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8469122 | 0.91 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL8380675 | 0.91 | TSHR (0.57) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL8384635 | 0.87 | TSHR (0.50) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL8386116 | 0.79 | TSHR (0.50) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL8385552 | 0.79 | TSHR (0.50) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL8381755 | 0.79 | TSHR (0.50) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL8381943 | 0.79 | TSHR (0.50) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL8386048 | 0.79 | TSHR (0.50) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL8381757 | 0.79 | TSHR (0.50) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL6420524 | 0.78 | TSHR (0.60) | TSHRTHRBCES2CES1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7888248-B2 | Method of producing large area SiC substrates | NORTHROP GRUMMAN SYSTEMS CORPORATION (US) | 2011-02-15 | — | — | US | claimed |
| EP-2174357-A1 | METHOD OF PRODUCING LARGE AREA SIC SUBSTRATES | Northrop Grumman Systems Corporation (US) | 2010-04-14 | — | — | EP | claimed |
| WO-2009011816-A1 | METHOD OF PRODUCING LARGE AREA SIC SUBSTRATES | NORTHROP GRUMMAN SYSTEMS CORPORATION (US) | 2009-01-22 | — | — | WO | claimed |
| US-20090014756-A1 | Method of producing large area SiC substrates | NORTHROP GRUMMAN SYSTEMS CORPORATION | 2009-01-15 | — | — | US | claimed |