Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.35 |
| ▸ | CES1 | P23141 | 3/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
| ▸ | PPARD | Q03181 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 4/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6419843 | 1.00 | TSHR (0.60) | TSHRALDH1A1TDP1THRBFAAH | |
| SCHEMBL8469122 | 0.86 | TSHR (0.57) | TSHRALDH1A1THRBCES2CES1 | |
| SCHEMBL8380675 | 0.86 | TSHR (0.57) | TSHRALDH1A1THRBCES2CES1 | |
| SCHEMBL9191869 | 0.84 | TSHR (0.60) | TSHRALDH1A1TDP1THRBFAAH | |
| SCHEMBL6422760 | 0.83 | — | — | |
| SCHEMBL8384635 | 0.83 | TSHR (0.50) | TSHRALDH1A1THRBCES2CES1 | |
| SCHEMBL31216189 | 0.79 | TSHR (0.68) | TSHRALDH1A1TDP1THRBFAAH | |
| SCHEMBL1248751 | 0.78 | TSHR (0.47) | TSHRALDH1A1THRBCES2CES1 | |
| SCHEMBL11742005 | 0.76 | TSHR (1.00) | TSHRALDH1A1TDP1THRBFAAH | |
| SCHEMBL5571322 | 0.76 | TSHR (1.00) | TSHRALDH1A1TDP1THRBFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6946537-B2 | Siloxane oligomers, a process for their production and their use | DEGUSSA AG (DE) | 2005-09-20 | — | — | US | disclosed |
| US-20040158090-A1 | Siloxane oligomers, a process for their production and their use | EVONIK DEGUSSA GMBH (DE) | 2004-08-12 | — | — | US | disclosed |
| US-20030018155-A1 | Siloxane oligomers, a process for their production and their use | DEGUSSA AG (DE) | 2003-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040158090-A1 | Siloxane oligomers, a process for their production and their use | SAAL1, RAD54L, RTF1 | TSHR 3723/4885ALDH1A1 216/4885TDP1 3208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.