Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | CPA3 | P15088 | 3/20 | 0.66 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.62 |
| ▸ | CPA1 | P15085 | 7/20 | 0.59 |
| ▸ | CPB1 | P15086 | 1/20 | 0.59 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL265514 | 0.90 | CYP1A2 (0.83) | CYP1A2CPA3FOLH1CPA1CPB1 | |
| SCHEMBL265063 | 0.90 | CYP1A2 (0.83) | CYP1A2CPA3FOLH1CPA1CPB1 | |
| SCHEMBL491524 | 0.90 | CYP1A2 (0.83) | CYP1A2CPA3FOLH1CPA1CPB1 | |
| SCHEMBL12494233 | 0.90 | CYP1A2 (0.83) | CYP1A2CPA3FOLH1CPA1CPB1 | |
| SCHEMBL6724759 | 0.90 | CYP1A2 (0.83) | CYP1A2CPA3FOLH1CPA1CPB1 | |
| SCHEMBL19821208 | 0.90 | CYP1A2 (0.83) | CYP1A2CPA3FOLH1CPA1CPB1 | |
| SCHEMBL28171699 | 0.89 | CYP1A2 (0.62) | CYP1A2CPA3FOLH1CPA1CPB1 | |
| Hydrochloric Acid SCHEMBL6717346 | 0.88 | CYP1A2 (0.79) | CYP1A2CPA3FOLH1CPA1CPB1 | |
| SCHEMBL12494702 | 0.87 | CYP1A2 (0.66) | CYP1A2CPA3FOLH1CPA1CPB1 | |
| SCHEMBL12494942 | 0.87 | CYP1A2 (0.66) | CYP1A2CPA3FOLH1CPA1CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9346852-B2 | Substituted adipic acid amides and uses thereof | BRISTOL-MYERS SCUIBB COMPANY (US) | 2016-05-24 | — | — | US | disclosed |
| US-9346852-B2 | Substituted adipic acid amides and uses thereof | BRISTOL-MYERS SCUIBB COMPANY (US) | 2016-05-24 | — | — | US | disclosed |
| US-9346852-B2 | Substituted adipic acid amides and uses thereof | BRISTOL-MYERS SCUIBB COMPANY (US) | 2016-05-24 | — | — | US | disclosed |
| US-20130345123-A1 | SUBSTITUTED ADIPIC ACID AMIDES AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-12-26 | — | — | US | disclosed |
| WO-2012125622-A1 | SUBSTITUTED ADIPIC ACID AMIDES AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-09-20 | — | — | WO | disclosed |
| WO-2012125622-A1 | SUBSTITUTED ADIPIC ACID AMIDES AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130345123-A1 | SUBSTITUTED ADIPIC ACID AMIDES AND USES THEREOF | NPY4R, ADIPOR1, NPY1R | CYP1A2 1432/4885CPA3 508/4885FOLH1 3242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.