Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.36 |
| ▸ | CHIT1 | Q13231 | 2/20 | 0.34 |
| ▸ | CHIA | Q9BZP6 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4934485 | 0.75 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3TDP1L3MBTL1 | |
| SCHEMBL28475644 | 0.72 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3CHIT1CHIA | |
| SCHEMBL10413244 | 0.72 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3MITFCA1 | |
| SCHEMBL6926417 | 0.72 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3MITFCA1 | |
| SCHEMBL22285003 | 0.72 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3MITFCA1 | |
| SCHEMBL12520753 | 0.70 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11734127 | 0.68 | SPHK1 (0.44) | SLC6A2SLC6A4SLC6A3TDP1L3MBTL1 | |
| SCHEMBL4149173 | 0.68 | CA1 (0.47) | SLC6A2SLC6A4SLC6A3TDP1L3MBTL1 | |
| SCHEMBL27588678 | 0.67 | HRH3 (0.46) | — | |
| SCHEMBL7812070 | 0.66 | SLC6A4 (0.38) | SLC6A2SLC6A4SLC6A3MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012119941-A1 | PEPTIDYL NITRILCOMPOUNDS AS PEPTIDASE INHIBITORS | PROZYMEX A/S (DK) | 2012-09-13 | — | — | WO | disclosed |