Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 4/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12499758 | 1.00 | KMT2A (0.40) | KMT2ALMNAHSP90AA1PIK3CALOXL2 | |
| SCHEMBL12499895 | 0.84 | CTBP2 (0.44) | KMT2ALMNAALDH1A1POLBMEN1 | |
| SCHEMBL12498657 | 0.84 | CTBP2 (0.44) | KMT2ALMNAALDH1A1POLBMEN1 | |
| SCHEMBL12498763 | 0.82 | CTBP2 (0.50) | KMT2APIK3CAKDM4EALDH1A1MEN1 | |
| SCHEMBL12498765 | 0.82 | CTBP2 (0.50) | KMT2APIK3CAKDM4EALDH1A1MEN1 | |
| SCHEMBL12498668 | 0.78 | PIK3CA (0.42) | PIK3CAIDO1PDPK1 | |
| SCHEMBL12498667 | 0.78 | PIK3CA (0.42) | PIK3CAIDO1PDPK1 | |
| Trifluoroacetic Acid SCHEMBL3399696 | 0.78 | SLC6A4 (0.46) | KMT2ALMNAHSP90AA1PIK3CACA2 | |
| SCHEMBL12499833 | 0.77 | MEN1 (0.51) | KMT2AALDH1A1IDO1MEN1MAPT | |
| SCHEMBL12499832 | 0.77 | MEN1 (0.51) | KMT2AALDH1A1IDO1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012103071-A2 | COMPOUNDS AND COMPOSITIONS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-08-02 | — | — | WO | disclosed |